May 27, 2017
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Tussionex Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking chlorpheniramine and hydrocodone (Tussionex)?

You should not take this medication if you are allergic to chlorpheniramine or hydrocodone.

Before taking chlorpheniramine and hydrocodone, tell your doctor if you are allergic to any drugs, or if you have:

  • asthma or other breathing disorder;
  • a history of head injury or brain tumor;
  • stomach or intestinal problems;
  • liver or kidney disease;
  • glaucoma;
  • urination problems or an enlarged prostate;
  • Addison's disease; or
  • underactive thyroid.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. Chlorpheniramine and hydrocodone may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether chlorpheniramine and hydrocodone passes into breast milk or if it could harm a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medicine.

Do not give chlorpheniramine and hydrocodone to a child younger than 6 years old.

How should I take chlorpheniramine and hydrocodone (Tussionex)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Do not take this medication more often than you doctor has prescribed. An overdose of chlorpheniramine and hydrocodone can cause life-threatening side effects.

Shake the oral solution (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid carefully with a marked measuring spoon or syringe, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not mix this medicine with any other liquid before taking it.

Chlorpheniramine and hydrocodone can be taken with food if it upsets your stomach.

Store chlorpheniramine and hydrocodone at room temperature away from moisture and heat.

Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Side Effects Centers

Tussionex - User Reviews

Tussionex User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Tussionex sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Allergies & Asthma

Improve treatments & prevent attacks.