May 23, 2017
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Tussionex Patient Information Including Side Effects

Brand Names: HyTan, Novasus, S-T Forte 2, TussiCaps, Tussionex PennKinetic

Generic Name: chlorpheniramine and hydrocodone (Pronunciation: KLOR fen IR a meen and HYE droe KOE done)

What is chlorpheniramine and hydrocodone (Tussionex)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Hydrocodone is a narcotic cough suppressant.

The combination of chlorpheniramine and hydrocodone is used to treat runny or stuffy nose, sneezing, and cough caused by the common cold or flu.

Chlorpheniramine and hydrocodone may also be used for other purposes not listed in this medication guide.

TussiCaps-8 mg-10 mg

capsule, white, imprinted with M, HP/CP 10/8

What are the possible side effects of chlorpheniramine and hydrocodone (Tussionex)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • weak or shallow breathing;
  • chest tightness;
  • painful urination;
  • urinating less than usual or not at all; or
  • confusion, hallucinations, or unusual behavior.

Less serious side effects may include:

  • dizziness, drowsiness, trouble concentrating;
  • mood changes, anxiety;
  • blurred vision;
  • constipation, nausea, vomiting, loss of appetite;
  • dry mouth or throat;
  • sweating; or
  • mild itching or skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the Tussionex (hydrocodone and chlorpheniramine) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about chlorpheniramine and hydrocodone (Tussionex)?

Do not take this medication more often than prescribed. An overdose of chlorpheniramine and hydrocodone can cause life-threatening side effects.

To be sure you get the correct dose, measure this medicine carefully with a marked measuring spoon or syringe, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Before you take chlorpheniramine and hydrocodone, tell your doctor if you have asthma or another breathing disorder, a history of head injury or brain tumor, stomach or intestinal problems, liver or kidney disease, glaucoma, urination problems or an enlarged prostate, Addison's disease, or underactive thyroid.

Chlorpheniramine and hydrocodone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol while using chlorpheniramine and hydrocodone. Alcohol may increase drowsiness and dizziness.

Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Do not give this medicine to a child younger than 6 years old.

Side Effects Centers

Tussionex - User Reviews

Tussionex User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Tussionex sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Allergies & Asthma

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