Tygacil (Tigecycline) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

February 10, 2012

Tygacil

Streptococcal Infections »

Group A streptococcal infections facts

Group A streptococci (GAS) are gram-positive coccal-shaped bacteria that produce beta-hemolysis (lysis of red blood cells producing clear or transparent areas) and appear as usually as a chain of two or more bacteria.
Group A Streptococcus (GAS) organisms are usually spread by direct human-to-human transfer. Occasionally, they can be spread by droplets or by a person touching items recently handled by an infected individual.
GAS can cause a wide range of diseases, but most notably, strep throat; other diseases (or complications) include scarlet fever, rheumatic fever, kidney damage, skin and wound infections and occasionally, necrotizing fasciitis and toxic shock syndrome.
Symptoms and signs of GAS disease are variable and are related to the body area that is undergoing the infection; for example, sore throat, throat erythema, and swollen lymph nodes in strep thro...

Read the Streptococcal Infections article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
next »

Tygacil User Reviews >>

Tygacil

Take the MRSA Quiz!

Strep or Sore Throat Slideshow Pictures

Infectious Mononucleosis Slideshow Pictures

font size

TYGACIL®
(tigecycline) for Injection for Intravenous Use

DRUG DESCRIPTION

TYGACIL (tigecycline) is a tetracycline derivative (a glycylcycline) for intravenous infusion. The chemical name of tigecycline is (4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-l,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-l,ll-dioxo-2-naphthacenecarboxamide. The empirical formula is C₂₉H₃₉N₅O₈ and the molecular weight is 585.65.

The following represents the chemical structure of tigecycline:

TYGACIL (tigecycline) Structural Formula Illustration"

TYGACIL (tigecycline) is an orange lyophilized powder or cake. Each TYGACIL vial contains 50 mg tigecycline lyophilized powder for reconstitution for intravenous infusion and 100 mg of lactose monohydrate. The pH is adjusted with hydrochloric acid, and if necessary sodium hydroxide. The product does not contain preservatives.

What are the possible side effects of tigecycline (Tygacil)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using tigecycline and call your doctor at once if you have any of these serious side effects:

diarrhea that is watery or bloody;
severe headache, pain behind your eyes, ringing or throbbing in your ears, problems with vision, and nausea or vomiting;
severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart...

Read All Potential Side Effects and See Pictures of Tygacil »

What are the precautions when taking tigecycline (Tygacil)?

Before using tigecycline, tell your doctor or pharmacist if you are allergic to it; or to tetracyclines (such as doxycycline, minocycline, tetracycline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe liver disease.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and...

Read All Potential Precautions of Tygacil »

Last reviewed on RxList: 8/5/2010
This monograph has been modified to include the generic and brand name in many instances.