Tygacil (Tigecycline) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

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E. Coli (0157:H7) »

E. coli 0157:H7 Facts

E. coli 0157:H7 is a gram-negative bacterium that can produce a bloody diarrhea due to toxins it secretes when it infects human intestinal tracts.
The symptoms of E. coli 0157:H7 infection may include a low fever, nausea, vomiting, stomach cramps, and bloody diarrhea.
E. coli 0157:H7 is notorious because it can cause additional complications in children and the elderly; renal failure, anemia, and dehydration especially for children (termed HUS or Hemolytic-uremic syndrome) and spontaneous bleeding, organ failures, and mental changes in the elderly (termed TTP or thrombotic thrombocytopenic purpura). Some of these patients develop disabilities or die.
Diagnosis is definitively made when E. coli 0157:H7 is isolated, usually from the patient's stool, and identified as serotype 0157 by immunologic tests.
Most E. coli 0157:H7 infections resolve s...

Read the E. Coli (0157:H7) article »

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Tygacil Patient Information including How Should I Take

What should I discuss with my healthcare provider before using tigecycline (Tygacil)?

Do not use this medication if you are allergic to tigecycline.

Before using tigecycline, tell your doctor if you have liver disease, or if you are allergic to antibiotics such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

Do not use this medication if you are pregnant. Babies born to mothers who use tigecycline during late pregnancy can have permanent tooth discoloration. Do not use tigecycline without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment.

Tigecycline can make birth control pills less effective. Use a second method of birth control while you are using tigecycline to keep from getting pregnant.

It is not known whether tigecycline passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Children younger than 8 years old should not use tigecycline. Tigecycline can cause permanent tooth discoloration.

How should I use tigecycline (Tygacil)?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

Tigecycline is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

This medication comes in a powder form that must be mixed with a liquid (diluent) such as sodium chloride or dextrose. After mixing, the liquid should appear as a yellow or orange color. Do not use the medication if it has changed colors to green or black, or if it has any particles in it. Call your doctor for a new prescription.

Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Use this medication for the entire length of time prescribed by your doctor. You may need to use the medication for as long as 2 weeks. Your symptoms may get better before the infection is completely treated. Tigecycline will not treat a viral infection such as the common cold or flu.

Store the unmixed powder medicine at room temperature away from moisture and heat. Once the medicine has been mixed, you may store it at room temperature as long as you use it within 24 hours.

Tigecycline mixed in an IV bag with sodium chloride or dextrose solution may be stored in a refrigerator and used within 45 hours.

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