"The U.S. Food and Drug Administration today approved Kadcyla (ado-trastuzumab emtansine), a new therapy for patients with HER2-positive, late-stage (metastatic) breast cancer.
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Tykerb Patient Information including If I Miss a Dose
In this Article
- What is lapatinib (Tykerb)?
- What are the possible side effects of lapatinib (Tykerb)?
- What is the most important information I should know about lapatinib (Tykerb)?
- What should I discuss with my health care provider before taking lapatinib (Tykerb)?
- How should I take lapatinib (Tykerb)?
- What happens if I miss a dose (Tykerb)?
- What happens if I overdose (Tykerb)?
- What should I avoid while taking lapatinib (Tykerb)?
- What other drugs will affect lapatinib (Tykerb)?
- Where can I get more information?
What happens if I miss a dose (Tykerb)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Tykerb)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking lapatinib (Tykerb)?
Grapefruit and grapefruit juice may interact with lapatinib and lead to potentially dangerous effects. Avoid using these products while taking lapatinib.
What other drugs will affect lapatinib (Tykerb)?
Many drugs can interact with lapatinib. Below is just a partial list. Tell your doctor if you are using:
- bosentan (Tracleer);
- conivaptan (Vaprisol);
- dexamethasone (Decadron, Hexadrol);
- digoxin (Lanoxin, Lanoxicaps);
- imatinib (Gleevec);
- isoniazid (for treating tuberculosis);
- midazolam (Versed);
- sirolimus (Rapamune) or tacrolimus (Prograf);
- St. John's wort;
- rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
- an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), pentamidine (NebuPent, Pentam), and others;
- an antidepressant such as nefazodone, amitriptylline (Elavil, Vanatrip), citalopram (Celexa), desipramine (Norpramin), fluoxetine (Prozac, Sarafem), and others;
- antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
- a barbiturate such as phenobarbital (Solfoton);
- heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), or verapamil (Calan, Covera, Isoptin, Verelan);
- heart rhythm medicine such as amiodarone (Cordarone, Pacerone), disopyramide (Norpace), propafenone (Rythmol), quinidine (Quin-G), sotalol (Betapace), and others;
- HIV or AIDS medications;
- medicine to prevent or treat nausea and vomiting, such as dolasetron (Anzemet) or ondansetron (Zofran);
- medicines to treat narcolepsy;
- medicines to treat psychiatric disorders, such as clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), or ziprasidone (Geodon);
- migraine headache medicine such as sumatriptan (Imitrex);
- narcotic medication such as methadone (Dolophine, Methadose); or
- seizure medication such as carbamazepine (Carbatrol, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).
This list is not complete and there are many other drugs that can cause serious or life-threatening medical problems if you take them together with lapatinib. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your doctor or pharmacist can provide more information about lapatinib.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 6.01. Revision date: 4/3/2012.
Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.
Additional Tykerb Information
- Tykerb Drug Interactions Center: lapatinib oral
- Tykerb Side Effects Center
- Tykerb Overview including Precautions
- Tykerb FDA Approved Prescribing Information including Dosage
Tykerb - User Reviews
Tykerb User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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