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In this Article

• What is acetaminophen and codeine (Tylenol-Codeine)?
• What are the possible side effects of acetaminophen and codeine (Tylenol-Codeine)?
• What is the most important information I should know about acetaminophen and codeine (Tylenol-Codeine)?
• What should I discuss with my healthcare provider before taking acetaminophen and codeine (Tylenol-Codeine)?
• How should I take acetaminophen and codeine (Tylenol-Codeine)?
• What happens if I miss a dose (Tylenol-Codeine)?
• What happens if I overdose (Tylenol-Codeine)?
• What should I avoid while taking acetaminophen and codeine (Tylenol-Codeine)?
• What other drugs will affect acetaminophen and codeine (Tylenol-Codeine)?
• Where can I get more information?

What happens if I miss a dose (Tylenol-Codeine)?

Since acetaminophen and codeine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose (Tylenol-Codeine)?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of acetaminophen and codeine can be fatal.

Overdose symptoms may include extreme drowsiness, sweating, pinpoint pupils, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), confusion, cold and clammy skin, fainting, weak pulse, seizure (convulsions), coma, blue lips, shallow breathing, or no breathing.

What should I avoid while taking acetaminophen and codeine (Tylenol-Codeine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Do not use any other cold, allergy, pain, or sleep medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as "APAP") is contained in many combination medicines. If you use certain products together you may accidentally use too much acetaminophen. Read the label of any other medicine you are using to see if it contains acetaminophen or APAP.

Avoid drinking alcohol while taking acetaminophen and codeine. Alcohol may increase your risk of liver damage while taking acetaminophen.

What other drugs will affect acetaminophen and codeine (Tylenol-Codeine)?

Before taking acetaminophen and codeine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, other pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by codeine.

Also tell your doctor if you are using any of the following drugs:

• glycopyrrolate (Robinul);
• mepenzolate (Cantil);
• atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
• bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
• a bronchodilator such as ipratroprium (Atrovent) or tiotropium (Spiriva); or
• irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).

This list is not complete and there may be other drugs that can interact with acetaminophen and codeine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about acetaminophen and codeine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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