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Tysabri

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Tysabri Patient Information including If I Miss a Dose

What happens if I miss a dose (Tysabri)?

Contact your doctor if you miss an appointment for your natalizumab injection.

What happens if I overdose (Tysabri)?

Seek emergency medical attention if you think you have received too much of this medicine. Symptoms of a natalizumab overdose are unknown.

What should I avoid while receiving natalizumab (Tysabri)?

Natalizumab can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Avoid contact with people who have colds, the flu, or other contagious illnesses. Contact your doctor immediately if you develop signs of infection.

What other drugs will affect natalizumab (Tysabri)?

Before receiving natalizumab, tell your doctor if you are taking any other medicines, especially those that may affect the immune system such as:

  • interferon (Roferon, Intron, Rebetron, Alferon, Avonex, Rebif, Betaseron, or Actimmune);
  • cyclosporine (Neoral, Sandimmune, Gengraf);
  • sirolimus (Rapamune), tacrolimus (Prograf);
  • basiliximab (Simulect), efalizumab (Raptiva), muromonab-CD3 (Orthoclone);
  • mycophenolate mofetil (CellCept);
  • azathioprine (Imuran), leflunomide (Arava), etanercept (Enbrel); or
  • if you are receiving chemotherapy or radiation treatments.

This list is not complete and there may be other drugs that can interact with natalizumab. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about natalizumab.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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