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Gout is a disease that results from an overload of uric acid in the body. This overload of uric acid leads to the formation of tiny crystals of urate that deposit in tissues of the body, especially the joints. When crystals form in the joints, it causes recurring attacks of joint inflammation (arthritis). Gout is considered a chronic and progressive disease. Chronic gout can also lead to deposits of hard lumps of uric acid in the tissues, particularly in and around the joints and may cause joint destruction, decreased kidney function, and kidney stones (nephrolithiasis).
Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. It is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid is a breakdown product of purines that are part of many foods we eat. An abnormality in handling uric acid can cause attacks of p...
Pharmacy Editor: Charles Patrick Davis, MD, PhD
Uloric (febuxostat) is a xanthine oxidase inhibitor used to trea thyperuricemia in patients with gout. Uloric is not available in a generic form. Side effects include arthralgias, nausea and rash.
Uloric (febuxostat) is available in tablets in strengths of 40 or 80 mg. Starting dosage is usually 40mg once daily. Serious side effects include cardiovascular events including myocardial infarction, liver enzyme abnormalities, weakness, numbness in extremities and shortness of breath. Uloric should not be used in patients treated with azathioprine or mercaptopurine. Use in pregnancy would have to outweigh risks to the fetus as such studies, including the presence of Uloric in breast milk of humans, has not been done. Safety and effectiveness in pediatric patients,18 years of age or less have not been done.
Our Uloric Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
ULORIC (febuxostat) is a xanthine oxidase (XO) inhibitor indicated for the chronic management of hyperuricemia in patients with gout.
ULORIC (febuxostat) is not recommended for the treatment of asymptomatic hyperuricemia.
Read the complete drug monograph for Uloric »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using febuxostat and call your doctor at once if you have any of these serious side effects:
Read the complete patient information for Uloric »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start febuxostat and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food, usually once daily or as directed by your doctor.
Dosage is based on your medical condition and response to treatment....
Read the complete consumer information for Uloric »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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