"The U.S. Food and Drug Administration today approved Krystexxa (pegloticase) to treat the painful condition known as gout in adults who do not respond to or who cannot tolerate conventional therapy.
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ULORIC was studied in healthy subjects in doses up to 300 mg daily for seven days without evidence of dose-limiting toxicities. No overdose of ULORIC was reported in clinical studies. Patients should be managed by symptomatic and supportive care should there be an overdose.
ULORIC is contraindicated in patients being treated with azathioprine or mercaptopurine [see DRUG INTERACTIONS].This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 11/16/2012
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