In this Article

• What is febuxostat (Uloric)?
• What are the possible side effects of febuxostat (Uloric)?
• What is the most important information I should know about febuxostat (Uloric)?
• What should I discuss with my healthcare provider before taking febuxostat (Uloric)?
• How should I take febuxostat (Uloric)?
• What happens if I miss a dose (Uloric)?
• What happens if I overdose (Uloric)?
• What should I avoid while taking febuxostat (Uloric)?
• What other drugs will affect febuxostat (Uloric)?
• Where can I get more information?

What should I discuss with my healthcare provider before taking febuxostat (Uloric)?

You should not use this medication if you are allergic to febuxostat, or if you are being treated with any of the following medications:

• azathioprine (Azasan, Imuran); or
• mercaptopurine (Purinethol).

To make sure you can safely take febuxostat, tell your doctor if you have any of these other conditions:

• kidney disease;
• liver disease;
• heart disease;
• a history of heart attack or stroke;
• cancer;
• Lesch-Nyhan syndrome; or
• if you have ever received an organ transplant (kidney, liver, lung, heart).

FDA pregnancy category C. It is not known whether febuxostat will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether febuxostat passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take febuxostat (Uloric)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

You may have an increase in gout symptom flares when you first start taking febuxostat. For best results, keep taking the medication as directed. Your doctor may prescribe other gout medications for you to use during the first 6 months of treatment with febuxostat.

To be sure this medication is helping your condition, your blood may need to be tested often. Visit your doctor regularly.

Store at room temperature away from moisture and heat.