Uloric (Febuxostat) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

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Gout »

What is gout? What is hyperuricemia?

Gout is a disease that results from an overload of uric acid in the body. This overload of uric acid leads to the formation of tiny crystals of urate that deposit in tissues of the body, especially the joints. When crystals form in the joints, it causes recurring attacks of joint inflammation (arthritis). Gout is considered a chronic and progressive disease. Chronic gout can also lead to deposits of hard lumps of uric acid in the tissues, particularly in and around the joints and may cause joint destruction, decreased kidney function, and kidney stones (nephrolithiasis).

Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. It is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid is a breakdown product of purines that are part of many foods we eat. An abnormality in handling uric acid can cause attacks of p...

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Uloric Patient Information Including Side Effects

Brand Names: Uloric

Generic Name: febuxostat (Pronunciation: fe BUX oh stat)

What is febuxostat (Uloric)?

Febuxostat reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.

Febuxostat is used to treat gout.

Febuxostat may also be used for other purposes not listed in this medication guide.

What are the possible side effects of febuxostat (Uloric)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using febuxostat and call your doctor at once if you have any of these serious side effects:

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, problems with vision, speech, or balance;
pale skin, easy bruising or bleeding;
hearing problems, ringing in your ears;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
blood in your urine; or
urinating less than usual;

Less serious side effects may include:

fever, chills, body aches, flu symptoms;
upset stomach;
dry mouth, thirst;
blurred vision;
dizziness, spinning sensation;
joint pain, swelling, or stiffness;
muscle pain; or
mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about febuxostat (Uloric)?

You should not use this medication if you are allergic to febuxostat, or if you are also being treated with azathioprine (Azasan, Imuran), mercaptopurine (Purinethol), or theophylline (Elixophyllin, TheoCap, Theochron, Uniphyl).

Before taking febuxostat, tell your doctor if you have kidney disease, liver disease, diabetes, heart disease, or high blood pressure.

You may have an increase in gout symptom flares when you first start taking febuxostat. For best results, keep taking the medication as directed. Your doctor may prescribe other gout medications for you to use during the first 6 months of treatment with febuxostat.

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using febuxostat.

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