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• Do not take ULTRACET® if you are allergic to any of its ingredients.
• If you develop signs of allergy such as a rash or difficulty breathing, stop taking ULTRACET® and contact your healthcare provider immediately.
• Do not take more than 4,000 milligrams of acetaminophen per day. Call your doctor if you took more than the recommended dose.
• Do not take ULTRACET® in combination with other tramadol or acetaminophen-containing products, including over-the-counter preparations.
• ULTRACET® may cause seizures and/or serotonin syndrome with concomitant use of serotonergic agents (including SSRIs, SNRIs, and triptans) or drugs that significantly reduce the metabolic clearance of tramadol.
• ULTRACET® may impair mental or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery.
• ULTRACET® should not be taken concomitantly with alcohol-containing beverages during the course of treatment with ULTRACET® .
• ULTRACET® should be used with caution when taking medications such as tranquilizers, hypnotics, or other opiate-containing analgesics.
• Inform the physician if you are pregnant, think you might become pregnant, or are trying to become pregnant (see PRECAUTIONS, Labor and Delivery).
• Understand the single-dose and 24-hour dose limit and the time interval between doses, since exceeding these recommendations can result in respiratory depression, seizures, hepatic toxicity, and death.

Last reviewed on RxList: 8/5/2011
This monograph has been modified to include the generic and brand name in many instances.