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Unithroid

Last reviewed on RxList: 5/16/2016
Unithroid Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 2/15/2016

Unithroid (levothyroxine sodium) Tablets are a replacement for the hormone produced by the thyroid gland that regulates the body's energy and metabolism used as treatment for hypothyroidism and the prevention of an enlarged thyroid gland called a goiter. Unithroid is available in generic form. Side effects of Unithroid include temporary hair loss, headache, sleep problems (insomnia), nervousness, irritability, fever, hot flashes, sweating, heart palpitations, changes in menstrual cycle, and appetite and weight changes.

Unithroid is taken in a single daily dose preferably half an hour to one hour before breakfast. Talk to your doctor about your individual recommended dosage amount. Unithroid may interact with medications such as Citracal or other calcium carbonates, iron supplements, Maalox or other antacids, as well as cholesterol-lowering drugs and should be taken at least 4 hours apart from taking these other medications. Tell your doctor about all medications and supplements you take. You should not use Unithroid if you have had a heart attack, thyroid disorder, or an adrenal gland disorder. Talk to your doctor if you are pregnant, become pregnant during treatment, or plan on breastfeeding as dosage of Unithroid may need to be increased. Do not stop taking this medication suddenly.

Our Unithroid (levothyroxine sodium) Tablets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Unithroid Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • headache;
  • sleep problems (insomnia);
  • feeling nervous or irritable;
  • fever, hot flashes, sweating;
  • pounding heartbeats or fluttering in your chest;
  • changes in your menstrual periods; or
  • appetite changes, weight changes.

Less serious side effects may include mild hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Unithroid (Levothyroxine Sodium)

Unithroid Professional Information

SIDE EFFECTS

Adverse reactions associated with levothyroxine therapy are primarily those of hyperthyroidism due to therapeutic overdosage (see PRECAUTIONS and OVERDOSAGE). They include the following:

General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating;

Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia;

Musculoskeletal: tremors, muscle weakness;

Cardiovascular: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest;

Respiratory: dyspnea;

Gastrointestinal: diarrhea, vomiting, abdominal cramps and elevation in liver function tests;

Dermatologic: hair loss; flushing;

Endocrine: decreased bone mineral density;

Reproductive: menstrual irregularities, impaired fertility.

Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised height.

Seizures have been reported rarely with the institution of levothyroxine therapy. Inadequate levothyroxine dosage will produce or fail to ameliorate the signs and symptoms of hypothyroidism.

Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various Gl symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.

Read the entire FDA prescribing information for Unithroid (Levothyroxine Sodium)

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© Unithroid Patient Information is supplied by Cerner Multum, Inc. and Unithroid Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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