Univasc (Moexipril) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

February 10, 2012

Univasc

Heart Attack »

What is a heart attack?

A heart attack (also known as a myocardial infarction) is the death of heart muscle from the sudden blockage of a coronary artery by a blood clot. Coronary arteries are blood vessels that supply the heart muscle with blood and oxygen. Blockage of a coronary artery deprives the heart muscle of blood and oxygen,causing injury to the heart muscle. Injury to the heart muscle causes chest pain and chest pressure sensation. If blood flow is not restored to the heart muscle within 20 to 40 minutes, irreversible death of the heart muscle will begin to occur. Muscle continues to die for six to eight hours at which time the heart attack usually is "complete." The dead heart muscle is eventually replaced by scar tissue.

Approximately one million Americans suffer a heart attack each year. Four hundred thousand of them die as a result of their heart attack.

What causes a ...

Read the Heart Attack article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
next »

Univasc User Reviews >>

Univasc

High Blood Pressure (Hypertension) Slideshow Pictures

Take the Salt Quiz!

Lowering Blood Pressure Exercise Tips Slideshow Pictures

font size

Univasc®
(moexipril hydrochloride) Tablets

USE IN PREGNANCY

When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, univasc® should be discontinued as soon as possible. See WARNINGS, Fetal/Neonatal Morbidity and Mortality.

DRUG DESCRIPTION

univasc® (moexipril hydrochloride), the hydrochloride salt of moexipril, has the empirical formula C₂₇H₃₄N₂O₇•HCl and a molecular weight of 535.04. It is chemically described as [3S[2[R*(R*)],3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, monohydrochloride. It is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat and its structural formula is:

nivasc® tablets
(moexipril hydrochloride) Structural Formula Illustration

Moexipril hydrochloride is a fine white to off-white powder. It is soluble (about 10% weight-tovolume) in distilled water at room temperature.

univasc® is supplied as scored, coated tablets containing 7.5 mg and 15 mg of moexipril hydrochloride for oral administration. In addition to the active ingredient, moexipril hydrochloride, the tablet core contains the following inactive ingredients: lactose, magnesium oxide, crospovidone, magnesium stearate and gelatin. The film coating contains hydroxypropyl cellulose, hypromellose, polyethylene glycol 6000, magnesium stearate, titanium dioxide, and ferric oxide.

What are the possible side effects of moexipril (Univasc)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

feeling light-headed, fainting;
urinating more or less than usual, or not at all;
fever, chills, body aches, flu symptoms;
tired feeling, muscle weakness, and pounding or uneven heartbeats;
chest pain;
swelling, rapid...

Read All Potential Side Effects and See Pictures of Univasc »

What are the precautions when taking moexipril (Univasc)?

Before taking moexipril, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors (e.g., benazepril, captopril); or if you have any other allergies (including an allergic reaction after exposure to certain membranes used for blood filtering). This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: history of an allergic reaction which included swelling of the face/lips/tongue/throat (angioedema).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease,...

Read All Potential Precautions of Univasc »

Last reviewed on RxList: 9/19/2011
This monograph has been modified to include the generic and brand name in many instances.