November 30, 2015
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Side Effects


Adverse effects of UREX (methenamine hippurate) have been reported in fewer than 3.5% of patients treated.

These reactions have included the following, in decreasing order of frequency: nausea, vomiting, and rarely puritus, rash, dysuria.

Children have received UREX (methenamine hippurate) at the recommended dosages as a prophylactic/suppressive regimen after initial treatment of acute episodes of pyuria. Side effects were encountered in only 1.1% of these children.

Read the Urex (methenamine hippurate) Side Effects Center for a complete guide to possible side effects


The concomitant administration of methenamine hippurate and sulfamethizole or sulfathiazole is liable to result in formation of a precipitate in the urine.

Drug/Laboratory Test Interactions. Methenamine causes spuriously elevated urinary 17- hydroxycorticosteroid and catecholamine levels.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 3/28/2008

Side Effects

Urex - User Reviews

Urex User Reviews

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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