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Uroxatral

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Uroxatral

UROXATRAL®
(alfuzosin HCl) Extended-release Tablet

DRUG DESCRIPTION

Each UROXATRAL extended-release tablet contains 10 mg alfuzosin hydrochloride as the active ingredient. Alfuzosin hydrochloride is a white to off-white crystalline powder that melts at approximately 240°C. It is freely soluble in water, sparingly soluble in alcohol, and practically insoluble in dichloromethane.

Alfuzosin hydrochloride is (R,S)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl) methylamino] propyl] tetrahydro-2-furancarboxamide hydrochloride. The empirical formula of alfuzosin hydrochloride is C19H27N5O4•HCl. The molecular weight of alfuzosin hydrochloride is 425.9. Its structural formula is:

UROXATRAL® (alfuzosin HCl)  Structural Formula Illustration

The tablet also contains the following inactive ingredients: colloidal silicon dioxide (NF), ethylcellulose (NF), hydrogenated castor oil (NF), hydroxypropyl methylcellulose (USP), magnesium stearate (NF), mannitol (USP), microcrystalline cellulose (NF), povidone (USP), and yellow ferric oxide (NF).

What are the possible side effects of alfuzosin (Uroxatral)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using alfuzosin and call your doctor at once if you have a serious side effect such as:

  • new or worsening chest pain;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • feeling like you might pass out; or
  • penis erection that is painful or lasts 4 hours or longer.

Less serious side effects may...

Read All Potential Side Effects and See Pictures of Uroxatral »

What are the precautions when taking alfuzosin hcl (Uroxatral)?

Before taking alfuzosin, tell your doctor or pharmacist if you are allergic to it; or to other alpha blockers such as doxazosin, prazosin, terazosin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: liver problems.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other prostate gland problems (e.g., prostate cancer), heart problems (e.g., angina, low blood pressure), kidney disease.

Alfuzosin may cause a condition that affects the heart rhythm...

Read All Potential Precautions of Uroxatral »

Last reviewed on RxList: 5/2/2014
This monograph has been modified to include the generic and brand name in many instances.

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Uroxatral - User Reviews

Uroxatral User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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