In this Article

• What is alfuzosin (Uroxatral)?
• What are the possible side effects of alfuzosin (Uroxatral)?
• What is the most important information I should know about alfuzosin (Uroxatral)?
• What should I discuss with my healthcare provider before taking alfuzosin (Uroxatral)?
• How should I take alfuzosin (Uroxatral)?
• What happens if I miss a dose (Uroxatral)?
• What happens if I overdose (Uroxatral)?
• What should I avoid while taking alfuzosin (Uroxatral)?
• What other drugs will affect alfuzosin (Uroxatral)?
• Where can I get more information?

What should I discuss with my healthcare provider before taking alfuzosin (Uroxatral)?

You should not use alfuzosin if you are allergic to it, or if you have:

• severe liver disease;
• if you are also taking similar medicines such as doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin); or
• if you are also using ketoconazole (Nizoral), itraconazole (Sporanox), or ritonavir (Norvir).

If you have any of these other conditions, you may need an alfuzosin dose adjustment or special tests:

• prostate cancer;
• liver disease;
• kidney disease;
• a personal or family history of Long QT syndrome;
• angina (chest pain);
• coronary artery disease (hardened arteries);
• a history of low blood pressure (even when caused by taking medications); or
• if you are taking certain medicines to treat HIV or AIDS.

Alfuzosin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using alfuzosin before surgery unless your surgeon tells you to.

Although this medication is not for use in women, alfuzosin is not expected to harm an unborn baby. If you are a woman using this medication, tell your doctor if you are pregnant or breast-feeding.

Alfuzosin is not for use in children.

How should I take alfuzosin (Uroxatral)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Alfuzosin is usually taken once a day, just after a meal. Try to take this medication at the same time each day. Do not take it on an empty stomach.

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.

Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it, or when you start taking it again. Call your doctor if you have severe dizziness or feel like you might pass out.

You may feel very dizzy when you first wake up. Be careful when standing or sitting up from a lying position.

Your blood pressure and prostate will need to be checked often. Visit your doctor regularly.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Store at room temperature away from moisture, heat, and light.