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Uvadex

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Uvadex

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UVADEX®
(methoxsalen) Sterile solution, 20 mcg/mL

CAUTION: READ THE UVAR® PHOTOPHERESIS SYSTEM OPERATOR'S MANUAL PRIOR TO PRESCRIBING OR DISPENSING THIS MEDICATION.

Uvadex® (methoxsalen) Sterile Solution should be used only by physicians who have special competence in the diagnosis and treatment of cutaneous T-cell lymphoma and who have special training and experience in the UVAR® or UVAR® XTS™ Photopheresis System. Please consult the appropriate Operator's Manual before using this product.

DRUG DESCRIPTION

Methoxsalen is a naturally occurring photoactive substance found in the seeds of the Ammi majus (Umbelliferae) plant. It belongs to a group of compounds known as psoralens or furocoumarins. The chemical name of methoxsalen is 9-methoxy-7H-furo[3,2-g][1]-benzopyran-7-one: it has the following structure:

UVADEX (Methoxsalen) Structural Formula Illustration

Each mL of UVAOEX® (methoxsalen, 8-methoxypsoralen) Sterile Solution contains methoxsalen 20 mcg, propylene glycol 50 mg, sodium chloride 8 mg, sodium acetate 1.75 mg, ethanol 0.05 mL, glacial acetic acid 0.0012 mL, and Water for Injection q.s.to 1.0 mL

UVAOEX® is used in combination with the UVAR® or UVAR® XTS™ Photopheresis System to extracorporeally treat leukocyte enriched buffy coat.

Last reviewed on RxList: 12/2/2008
This monograph has been modified to include the generic and brand name in many instances.

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