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Side effects of photopheresis (UVADEX® (methoxsalen) used with the UVAR® Photopheresis System) were primarily related to hypotension secondary to changes in extra corporeal volume ( > 1%), In study CTCL3 (UVADEX® (methoxsalen) ), six serious cardiovascular adverse experiences were reported in five patients (5/51,10%), Five of these six events were not related to photopheresis and did not interfere with the scheduled photopheresis treatments. One patient (1/51,2%) with ischemic heart disease had an arrhythmia after the first day of photopheresis that was resolved the next day. Six infections were also reported in five patients, Two of the six events were Hick man catheter infections in one patient, which did not interrupt the scheduled photopheresis, The other four infections were not related to photopheresis and did not interfere with scheduled treatments.

See WARNINGS Section.

Last reviewed on RxList: 12/2/2008
This monograph has been modified to include the generic and brand name in many instances.