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Uvadex Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Uvadex (methoxsalen) Sterile Solution is a psoralen photosensitizer used to treat cutaneous T-cell lymphoma (CTCL) and is used in a procedure called photopheresis. Common side effects include dizziness, headache, weakness, leg cramps, or bitter/sour taste in the mouth.
Dosage of Uvadex is based on your medical condition, the amount of white blood cells collected, and response to treatment. Uvadex may interact with anthralin, bacteriostatic soaps, coal tar, certain dyes (methylene blue, toluidine blue, rose bengal, methyl orange), griseofulvin, nalidixic acid, phenothiazines, antibiotics, and diuretics. Tell your doctor all medications and supplements you use. Uvadex is not recommended for use during pregnancy. Consult your doctor to discuss using at least 2 forms of birth control (e.g., condoms, birth control pills) while using this medication. If you become pregnant or think you may be pregnant, tell your doctor. It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breastfeeding while using this drug is not recommended.
Our Uvadex (methoxsalen) Sterile Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Uvadex Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
This medication will make your eyes and skin more sensitive to the sun. (See also Precautions section.) Tell your doctor immediately if any of these signs of sun sensitivity occur: swollen/red/blistering/peeling skin, vision changes.
Tell your doctor right away if you have any serious side effects, including: depression, swollen ankles/feet, new/unusual skin sores, irregular heartbeat.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Uvadex (Methoxsalen)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Uvadex FDA Prescribing Information: Side Effects
Side effects of photopheresis (UVADEX™ used with the THERAKOS™ Photopheresis System) were primarily related to hypotension secondary to changes in extracorporeal volume ( > 1%). In study CTCL 3 (UVADEX™), six serious cardiovascular adverse experiences were reported in five patients (5/51, 10%). Five of these six events were not related to photopheresis and did not interfere with the scheduled photopheresis treatments. One patient (1/51, 2%) with ischemic heart disease had an arrhythmia after the first day of photopheresis that was resolved the next day. Six infections were also reported in five patients. Two of the six events were Hickman catheter infections in one patient, which did not interrupt the scheduled photopheresis. The other four infections were not related to photopheresis and did not interfere with scheduled treatments.
An analysis of postmarketing data shows the following events occurred with an incidence of < 0.01%: rash, allergic reaction, pyrexia, nausea, dysgeusia.
Read the entire FDA prescribing information for Uvadex (Methoxsalen)
Additional Uvadex Information
- Uvadex Drug Interactions Center: methoxsalen inj
- Uvadex Side Effects Center
- Uvadex Overview including Precautions
- Uvadex FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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