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Hemofiltration and hemoperfusion with polysulfone resin have been reported to result in increased vancomycin clearance. The median lethal intravenous dose is 319 mg/kg in rats and 400 mg/kg in mice.
To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. Telephone numbers of certified poison control centers are listed in the Physicians' Desk Reference (PDR). In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient.
Last reviewed on RxList: 2/7/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Vancomycin Hydrochloride Information
- Vancomycin Hydrochloride Drug Interactions Center: vancomycin iv
- Vancomycin Hydrochloride Side Effects Center
- Vancomycin Hydrochloride Overview including Precautions
- Vancomycin Hydrochloride FDA Approved Prescribing Information including Dosage
Vancomycin Hydrochloride - User Reviews
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