Vancomycin Hydrochloride (Vancomycin Hydrochloride Injection) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Vancomycin Injection

Impetigo »

What is impetigo? What causes impetigo?

Impetigo (pronounced im-puh-TIE-go) is a contagious, superficial infection of the skin caused by staphylococcus (Staph) and streptococcus (Strep) bacteria. Impetigo is more common in children (especially 2- to 5-year-olds) than in adults. Impetigo is most likely to occur in warm and humid environments and is most commonly spread by close contact (such as family members).

What are the types of impetigo, and what are impetigo symptoms and signs? What does impetigo look like?

There are two kinds of impetigo:

Non-bullous impetigo: This is the common form, caused by both Staph and Strep bacteria. This form initially presents as small red papules similar to insect bites. These lesions rapidly evolve to small blisters and then to pustules that finally scab over with a characteristic honey-colored crust. This entire process takes about one week. These lesions often st...

Read the Impetigo article »

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Vancomycin Injection, USP in GALAXY Plastic Container (PL 2040)
For Intravenous Use Only

To reduce the development of drug-resistant bacteria and maintain the effectiveness of vancomycin and other antibacterial drugs, vancomycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DRUG DESCRIPTION

Vancomycin Injection, USP in the GALAXY plastic container (PL 2040) contains vancomycin, added as Vancomycin Hydrochloride, USP. It is a tricyclic glycopeptide antibiotic derived from Amycolatopsis orientalis (formerly Nocardia orientalis). The molecular formula is C₆₆H₇₅Cl₂N₉O₂₄ • HCl and the molecular weight is 1,485.71. 500 mg of the base is equivalent to 0.34 mmol. Vancomycin hydrochloride has the following structural formula:

Vancomycin Structural Formula Illustration

Vancomycin Injection, USP in the GALAXY plastic container (PL 2040) is a frozen, isoosmotic, sterile, nonpyrogenic premixed 100 mL, 150 mL, or 200 mL solution containing 500 mg, 750 mg, or 1 g Vancomycin respectively as Vancomycin hydrochloride. Each 100 mL of solution contains approximately 5 g of Dextrose Hydrous, USP. The pH of the solution may have been adjusted with hydrochloric acid and/or sodium hydroxide. Thawed solutions have a pH in the range of 3.0 to 5.0. After thawing to room temperature, this solution is intended for intravenous use only.

This GALAXY container is fabricated from a specially designed multilayer plastic (PL 2040). Solutions are in contact with the polyethylene layer of this container and can leach out certain chemical components of the plastic in very small amounts within the expiration period. The suitability of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by tissue culture toxicity studies.

Last reviewed on RxList: 2/7/2012
This monograph has been modified to include the generic and brand name in many instances.