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Vancomycin Injection, USP in GALAXY
Plastic Container (PL 2040)
For Intravenous Use Only
To reduce the development of drug-resistant bacteria and maintain the effectiveness of vancomycin and other antibacterial drugs, vancomycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Vancomycin Injection, USP in the GALAXY plastic container (PL 2040) contains vancomycin, added as Vancomycin Hydrochloride, USP. It is a tricyclic glycopeptide antibiotic derived from Amycolatopsis orientalis (formerly Nocardia orientalis). The molecular formula is C66H75Cl2N9O24 • HCl and the molecular weight is 1,485.71. 500 mg of the base is equivalent to 0.34 mmol. Vancomycin hydrochloride has the following structural formula:
Vancomycin Injection, USP in the GALAXY plastic container (PL 2040) is a frozen, isoosmotic, sterile, nonpyrogenic premixed 100 mL, 150 mL, or 200 mL solution containing 500 mg, 750 mg, or 1 g Vancomycin respectively as Vancomycin hydrochloride. Each 100 mL of solution contains approximately 5 g of Dextrose Hydrous, USP. The pH of the solution may have been adjusted with hydrochloric acid and/or sodium hydroxide. Thawed solutions have a pH in the range of 3.0 to 5.0. After thawing to room temperature, this solution is intended for intravenous use only.
This GALAXY container is fabricated from a specially designed multilayer plastic (PL 2040). Solutions are in contact with the polyethylene layer of this container and can leach out certain chemical components of the plastic in very small amounts within the expiration period. The suitability of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by tissue culture toxicity studies.
Last reviewed on RxList: 2/7/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Vancomycin Hydrochloride Information
Vancomycin Hydrochloride - User Reviews
Vancomycin Hydrochloride User Reviews
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