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(metronidazole) Vaginal Gel, 0.75% for Intravaginal Use.


VANDAZOLE (metronidazole vaginal gel, 0.75%) is the vaginal dosage form of the nitroimidazole antimicrobial metronidazole at a concentration of 0.75%. Chemically, metronidazole is a 2-methyl-5-nitroimidazole-1-ethanol.

VANDAZOLE® (metronidazole vaginal gel, 0.75%)  Structural Formula Illustration

C6H9N3O3     M.W. 171.16

VANDAZOLE is a colorless to yellow gel, containing metronidazole at a concentration of 7.5 mg/g (0.75%). The gel also contains edetate disodium, hypromellose, methylparaben, propylene glycol, propylparaben, purified water, and sodium hydroxide (to adjust pH).

Each applicator full of 5 grams of vaginal gel contains approximately 37.5 mg of metronidazole.

What are the possible side effects of metronidazole vaginal (MetroGel-Vaginal, Vandazole)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Rare but serious side effects may include:

  • seizure (convulsions); or
  • numbness, burning, pain, or tingly feeling in your hands or feet.

Less serious side effects may include:

  • mild burning or stinging when the medication is applied;
  • pelvic pain or cramps;
  • loss of appetite, constipation, upset stomach, vomiting;
  • dizziness,...

Read All Potential Side Effects and See Pictures of Vandazole »

Last reviewed on RxList: 3/29/2011
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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