"Investigators from the Women's Health Initiative (WHI) Hormone Trials are reaffirming conclusions that hormone therapy is not recommended for the prevention of chronic disease, but may remain a reasonable option for the short-term management "...
(metronidazole) Vaginal Gel, 0.75% for Intravaginal Use.
VANDAZOLE (metronidazole vaginal gel, 0.75%) is the vaginal dosage form of the nitroimidazole antimicrobial metronidazole at a concentration of 0.75%. Chemically, metronidazole is a 2-methyl-5-nitroimidazole-1-ethanol.
C6H9N3O3 M.W. 171.16
VANDAZOLE is a colorless to yellow gel, containing metronidazole at a concentration of 7.5 mg/g (0.75%). The gel also contains edetate disodium, hypromellose, methylparaben, propylene glycol, propylparaben, purified water, and sodium hydroxide (to adjust pH).
Each applicator full of 5 grams of vaginal gel contains approximately 37.5 mg of metronidazole.
What are the possible side effects of metronidazole vaginal (MetroGel-Vaginal, Vandazole)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Rare but serious side effects may include:
- seizure (convulsions); or
- numbness, burning, pain, or tingly feeling in your hands or feet.
Less serious side effects may include:
- mild burning or stinging when the medication is applied;
- pelvic pain or cramps;
- loss of appetite, constipation, upset stomach, vomiting;
Last reviewed on RxList: 3/29/2011
This monograph has been modified to include the generic and brand name in many instances.
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