"A sharp rise in the incidence of congenital syphilis between 2012 and 2014 parallels a national increase in primary and secondary syphilis among women during the same period, according to the Centers for Disease Control and Prevention (CDC). The "...
(metronidazole) Vaginal Gel, 0.75% for Intravaginal Use.
VANDAZOLE (metronidazole vaginal gel, 0.75%) is the vaginal dosage form of the nitroimidazole antimicrobial metronidazole at a concentration of 0.75%. Chemically, metronidazole is a 2-methyl-5-nitroimidazole-1-ethanol.
C6H9N3O3 M.W. 171.16
VANDAZOLE is a colorless to yellow gel, containing metronidazole at a concentration of 7.5 mg/g (0.75%). The gel also contains edetate disodium, hypromellose, methylparaben, propylene glycol, propylparaben, purified water, and sodium hydroxide (to adjust pH).
Each applicator full of 5 grams of vaginal gel contains approximately 37.5 mg of metronidazole.
What are the possible side effects of metronidazole vaginal (MetroGel-Vaginal, Vandazole)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Rare but serious side effects may include:
- seizure (convulsions); or
- numbness, burning, pain, or tingly feeling in your hands or feet.
Less serious side effects may include:
- mild burning or stinging when the medication is applied;
- pelvic pain or cramps;
- loss of appetite, constipation, upset stomach, vomiting;
Last reviewed on RxList: 3/29/2011
This monograph has been modified to include the generic and brand name in many instances.
Additional Vandazole Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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