"A sharp rise in the incidence of congenital syphilis between 2012 and 2014 parallels a national increase in primary and secondary syphilis among women during the same period, according to the Centers for Disease Control and Prevention (CDC). The "...
The use of VANDAZOLE (metronidazole vaginal gel) is contraindicated in patients with a history of hypersensitivity to metronidazole, other nitroimidazole derivatives, or parabens. Reported reactions include urticaria; erythematous rash; Stevens-Johnson Syndrome, toxic epidermal necrolysis, flushing; nasal congestion; dryness of the mouth, vagina, or vulva; fever; pruritus; fleeting joint pains [see ADVERSE REACTIONS].
Psychotic Reaction with Disulfiram
Use of oral metronidazole is associated with psychotic reactions in alcoholic patients who were using disulfiram concurrently. Do not administer VANDAZOLE (metronidazole vaginal gel) to patients who have taken disulfiram within the last two weeks [see ADVERSE REACTIONS].
Interaction with Alcohol
Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing [see ADVERSE REACTIONS]. Discontinue alcohol consumption during and for at least three days after therapy with VANDAZOLE (metronidazole vaginal gel) .This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 4/4/2011
Additional Vandazole Information
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