"How long a young adult is obese may affect that person's heart disease risk in middle age, according to new research. The finding suggests that not only preventing but also delaying the onset of obesity can help reduce heart disease later in life"...
Although no data on overdosage in humans are available, VAPRISOL has been administered as a 20 mg loading dose on Day 1 followed by continuous infusion of 80 mg/day for 4 days in hyponatremia patients and up to 120 mg/day for 2 days in CHF patients. No new toxicities were identified at these higher doses, but adverse events related to the pharmacologic activity of VAPRISOL, e.g. hypotension and thirst, occurred more frequently at these higher doses.
In case of overdose, based on expected exaggerated pharmacological activity, symptomatic treatment with frequent monitoring of vital signs and close observation of the patient is recommended.
VAPRISOL is contraindicated in patients with hypovolemic hyponatremia.
Coadministration with Potent CYP3A Inhibitors
The coadministration of VAPRISOL with potent CYP3A inhibitors, such as ketoconazole, itraconazole, clarithromycin, ritonavir, and indinavir, is contraindicated [see DRUG INTERACTIONS].
Known Allergy to Corn or Corn Products
Solutions containing dextrose are contraindicated in patients with known allergy to corn or corn products.
Last reviewed on RxList: 2/28/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Vaprisol Information
Report Problems to the Food and Drug Administration
Get the latest treatment options.