Recommended Topic Related To:

Vascor

"Potential drug treatments are tested on paper, in laboratories and eventually in thousands of people. But every drug that goes through this cycle “ every drug that FDA approves “ carries some risk. One of the first lines of defense against "...

Vascor

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

VASCOR
(bepridil hydrochloride)

DRUG DESCRIPTION

VASCOR (bepridil hydrochloride) is a calcium channel blocker that has well characterized anti-anginal properties and known but poorly characterized type 1 anti-arrhythmic and anti-hypertensive properties. It has inhibitory effects on both the slow calcium and fast sodium inward currents in myocardial and vascular smooth muscle, interferes with calcium binding to calmodulin, and blocks both voltage and receptor operated calcium channels. It is not related chemically to other calcium channel blockers such as diltiazem hydrochloride, nifedipine and verapamil hydrochloride.

Bepridil hydrochloride monohydrate is a white to off-white, crystalline powder with a bitter taste. It is slightly soluble in water, very soluble in ethanol, methanol and chloroform, and freely soluble in acetone. The molecular weight of bepridil hydrochloride monohydrate is 421.02. Its molecular formula is C 24 H 34 N 2 O·HCl·H 2 O.

   (±)-(beta)-[(2-Methylpropoxy)methyl]-N-phenyl- N -(phenyl- methyl)-1-pyrrolidineethanamine monohydrochloride monohydrate

VASCOR (bepridil) is available as film-coated tablets for oral use containing 200, 300, or 400 mg of bepridil hydrochloride monohydrate. Inactive ingredients: hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, silicon dioxide, pregelatinized corn starch, corn starch, titanium dioxide, FD&C Blue #1.

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

A A A

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.