Brand Names: Vaseretic 10-25, Vaseretic 5-12.5

Generic Name: hydrochlorothiazide and enalapril (Pronunciation: HYE droe KLOR oh THYE a zide and en AL e pril)

• What is hydrochlorothiazide and enalapril (Vaseretic)?
• What are the possible side effects of hydrochlorothiazide and enalapril (Vaseretic)?
• What is the most important information I should know about hydrochlorothiazide and enalapril (Vaseretic)?
• What should I discuss with my healthcare provider before taking hydrochlorothiazide and enalapril (Vaseretic)?
• How should I take hydrochlorothiazide and enalapril (Vaseretic)?
• What happens if I miss a dose (Vaseretic)?
• What happens if I overdose (Vaseretic)?
• What should I avoid while taking hydrochlorothiazide and enalapril (Vaseretic)?
• What other drugs will affect hydrochlorothiazide and enalapril (Vaseretic)?
• Where can I get more information?

What is hydrochlorothiazide and enalapril (Vaseretic)?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Enalapril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Enalapril lowers blood pressure and also relieves symptoms of fluid retention.

The combination of hydrochlorothiazide and enalapril is used to treat hypertension (high blood pressure).

Hydrochlorothiazide and enalapril may also be used for other purposes not listed in this medication guide.

Enalapril-HCT 10 mg-25 mg-MYL

round, white, imprinted with 723, M

Enalapril-HCTZ 10 mg-25 mg-MYL

round, white, imprinted with M, 712

Enalapril-HCTZ 10 mg-25 mg-TEV

oblong, brown, imprinted with 93, 1052

Enalapril-HCTZ 10-25 mg-APO

round, brown, imprinted with APO, 10 25

Enalapril-HCTZ 5 mg-12.5 mg-TEV

oblong, white, imprinted with 93, 1044

Enalapril-HCTZ 5-12.5 mg-APO

round, brown, imprinted with APO, 5 12.5

Enalapril-HCTZ-5mg-12.5mg-TAR

oblong, white, imprinted with T4

Vaseretic 10-25

hexagonal, pink, imprinted with VASERETIC, MSD 720

What are the possible side effects of hydrochlorothiazide and enalapril (Vaseretic)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
• low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
• dry mouth, thirst, nausea, vomiting;
• feeling weak, drowsy, restless, or light-headed;
• a red, blistering, peeling skin rash;
• jaundice (yellowing of the skin or eyes);
• urinating less than usual or not at all;
• swelling, weight gain, feeling short of breath; or
• fever, chills, body aches, flu symptoms.

Less serious side effects may include:

• cough;
• dizziness, headache, tired feeling;
• blurred vision;
• diarrhea, constipation, upset stomach; or
• mild skin rash, increased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about hydrochlorothiazide and enalapril (Vaseretic)?

Do not use this medication if you are unable to urinate.

You should not use this medication if you are allergic to other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

Before taking hydrochlorothiazide and enalapril, tell your doctor if you have kidney disease (or are on dialysis), liver disease, congestive heart failure, asthma, gout, lupus, diabetes, or an allergy to sulfa drugs.

Enalapril can cause birth defects in the baby if you take the medication during pregnancy. Do not use hydrochlorothiazide and enalapril without telling your doctor if you are pregnant or planning a pregnancy.

Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking hydrochlorothiazide and enalapril, unless your doctor has told you to.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking other diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking hydrochlorothiazide and enalapril. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.