Vasocidin (Sulfacetamide and Prednisolone) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

Vasocidin

Eye Care »

What is the structure of the eye?

The eyes are complex sensory organs. About 85% of the total sensory input to our brains originates from our sense of sight, while the other 15% comes from the other four senses of hearing, smell, touch, and taste. The eyes are designed to optimize vision under conditions of varying light. Their location, on the outside of the face, makes them susceptible to trauma, environmental chemicals and particles, and infectious agents. The eyelids and the position of the eye within the bony orbital cavity are the major protective mechanism for the eye.

The eye itself has the shape of a sphere measuring about 1 inch in diameter. It consists of a clear, transparent dome at the front (the cornea) that is surrounded by the white of the eyeball (the sclera). The iris of the eye is the circular, colored portion within the eye, and behind the cornea, and the pupil is the central opening within the iris. Behind the iris and pupil is the e...

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Vasocidin

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VASOCIDIN
(prednisolone sodium phosphate and sulfacetamide sodium) Solution

DRUG DESCRIPTION

VASOCIDIN (sulfacetamide and prednisolone) is a sterile topical ophthalmic solution combining an anti-infective and an adrenocortical steroid having the following composition:

Sulfacetamide Sodium 100 mg/mL
(bacteriostatic antibacterial)

Prednisolone Sodium Phosphate 2.5mg/mL
(equivalent to Prednisolone Phosphate 2.3 mg/mL)
(adrenocortical steroid/anti-inflammatory)

In a solution containing edetate disodium, poloxamer 407, boric acid, purified water, preserved with thimerosal 0.1 mg/mL. Hydrochloric acid and/or sodium hydroxide added to adjust pH.

The chemical name for sulfacetamide sodium is Acetamide, N-[(4-aminophenyl) sulfonyl]-, monosodium salt, monohydrate.

The chemical name for prednisolone sodium phosphate is 11β, 17, 21-trihydroxypregna-1,4-diene-3,20-dione, 21-(disodium phosphate).

They have the following chemical structures

Sulfacetamide Sodium

Prednisolone Sodium Phosphate

What are the precautions when taking sulfacetamide and prednisolone (Vasocidin)?

Before using sulfacetamide/prednisolone, tell your doctor or pharmacist if you are allergic to it; or to sulfa drugs (e.g., sulfamethoxazole), corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye problems (e.g., glaucoma, severely dry eyes), eye surgeries (e.g., cataract surgery), diabetes.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until...

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Last reviewed on RxList: 4/8/2009
This monograph has been modified to include the generic and brand name in many instances.