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Vasocidin

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Vasocidin

VASOCIDIN
(prednisolone sodium phosphate and sulfacetamide sodium) Solution

DRUG DESCRIPTION

VASOCIDIN (sulfacetamide and prednisolone) is a sterile topical ophthalmic solution combining an anti-infective and an adrenocortical steroid having the following composition:

Sulfacetamide Sodium 100 mg/mL
  (bacteriostatic antibacterial)

Prednisolone Sodium Phosphate 2.5mg/mL
  (equivalent to Prednisolone Phosphate 2.3 mg/mL)
  (adrenocortical steroid/anti-inflammatory)

In a solution containing edetate disodium, poloxamer 407, boric acid, purified water, preserved with thimerosal 0.1 mg/mL. Hydrochloric acid and/or sodium hydroxide added to adjust pH.

The chemical name for sulfacetamide sodium is Acetamide, N-[(4-aminophenyl) sulfonyl]-, monosodium salt, monohydrate.

The chemical name for prednisolone sodium phosphate is 11β, 17, 21-trihydroxypregna-1,4-diene-3,20-dione, 21-(disodium phosphate).

They have the following chemical structures

Sulfacetamide Sodium

Sulfacetamide Sodium Structural Formula Illustration

Prednisolone Sodium Phosphate

Prednisolone Sodium Phosphate Structural Formula Illustration

What are the precautions when taking sulfacetamide and prednisolone (Vasocidin)?

Before using sulfacetamide/prednisolone, tell your doctor or pharmacist if you are allergic to it; or to sulfa drugs (e.g., sulfamethoxazole), corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye problems (e.g., glaucoma, severely dry eyes), eye surgeries (e.g., cataract surgery), diabetes.

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until...

Read All Potential Precautions of Vasocidin »

Last reviewed on RxList: 4/8/2009
This monograph has been modified to include the generic and brand name in many instances.

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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