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Vasocidin Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Vasocidin (prednisolone sodium phosphate and sulfacetamide sodium) Solution is a topical ophthalmic solution combining a steroid (prednisolone) and an antibiotic (sulfacetamide) used to prevent or treat eye infections and to treat swelling in the eye. Common side effects include temporary stinging or burning of your eyes for a minute or two when applied. Eye discomfort, dry eyes, tearing, itching, or redness may occur.
The dose of Vasocidin is to instill two drops topically in the eye(s) every four hours. Vasocidin may interact with gentamicin, local anesthetics, and preparations that contain silver. Tell your doctor all medications and supplements you use. During pregnancy, Vasocidin should be used only if prescribed. It is unknown if the medications in this product pass into breast milk. Consult your doctor before breastfeeding.
Our Vasocidin (prednisolone sodium phosphate and sulfacetamide sodium) Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Vasocidin Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Use of this medication for prolonged or repeated periods may result in a new type of eye infection (e.g., viral, fungal). Do not use it for longer than prescribed. Contact your doctor if you notice new or worsening symptoms.
Tell your doctor immediately if any of these unlikely but serious side effects occur: vision changes, eye pain, staining of the eyes.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, signs of infection (e.g., fever, persistent sore throat), easy bleeding/bruising, yellowing of the eyes/skin, dark urine.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Vasocidin (Sulfacetamide and Prednisolone)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Vasocidin FDA Prescribing Information: Side Effects
Adverse reactions have occurred with corticosteroid/anti-infective combination drugs which can be attributed to the corticosteroid component, the anti-infective component, or the combination. Exact incidence figures are not available since no denominator of treated patients is available.
Reactions occurring most often from the presence of the anti-infective ingredient are allergic sensitizations. Fatalities have occurred, although rarely, due to severe reactions to sulfonamides including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias (see WARNINGS).
Sulfacetamide sodium may cause local irritation.
The reactions due to the corticosteroid component in decreasing order of frequency are: elevation of intraocular pressure (IOP) with possible development of glaucoma, and infrequent optic nerve damage; posterior subcapsular cataract formation; and delayed wound healing.
Corticosteroid-containing preparations can also cause acute anterior uveitis or perforation of the globe. Mydriasis, loss of accommodation and ptosis have occasionally been reported following local use of corticosteroids.
The development of secondary infection has occurred after use of combinations containing corticosteroids and antimicrobials. Fungal and viral infections of the cornea are particularly prone to develop coincidentally with long-term applications of corticosteroid. The possibility of fungal invasion must be considered in any persistent corneal ulceration where corticosteroid treatment has been used.
Secondary bacterial ocular infection following suppression of host responses also occurs.
Read the entire FDA prescribing information for Vasocidin (Sulfacetamide and Prednisolone)
Additional Vasocidin Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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