"The largest study to date to focus on patients with colorectal cancer (CRC) with deficient DNA mismatch repair (dMMR) has found that adjuvant therapy with fluoropyrimidine combined with oxaliplatin (Eloxatin, Sanofi-Aventis), but not fluor"...
Vectibix Patient Information Including Side Effects
Brand Names: Vectibix
Generic Name: panitumumab (Pronunciation: pan i TUE moo mab)
- What is panitumumab (Vectibix)?
- What are the possible side effects of panitumumab (Vectibix)?
- What is the most important information I should know about panitumumab (Vectibix)?
- What should I discuss with my health care provider before receiving panitumumab (Vectibix)?
- How is panitumumab given (Vectibix)?
- What happens if I miss a dose (Vectibix)?
- What happens if I overdose (Vectibix)?
- What should I avoid while taking panitumumab (Vectibix)?
- What other drugs will affect panitumumab (Vectibix)?
- Where can I get more information?
What is panitumumab (Vectibix)?
Panitumumab is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Panitumumab is used to treat metastatic colorectal cancer that has progressed after treatment with other chemotherapy.
Panitumumab may also be used for purposes not listed in this medication guide.
What are the possible side effects of panitumumab (Vectibix)?
Some people receiving a panitumumab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, itchy, or have a fever, chills, or trouble breathing during the injection.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some of the side effects of panitumumab may not appear when you first start using the medication. Severe skin or eye reactions may occur up to 2 weeks after the start of your treatment. These effects may not clear up for weeks or even months after you stop receiving panitumumab.
Call your doctor at once if you have a serious side effect such as:
- acne, dryness, peeling, cracking, bleeding, oozing, pus, or any other signs of skin infection;
- swelling or infection around your fingernails or toenails.
- vision changes;
- sudden chest pain or discomfort, wheezing, dry cough or hack, feeling short of breath on exertion;
- feeling weak or tired, loss of appetite, rapid weight loss;
- swelling in your face, hands, ankles, or feet;
- feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
- white patches or sores inside your mouth or on your lips;
- drowsiness, restless feeling, confusion, muscle stiffness, fast or uneven heart rate;
- redness, swelling, or irritation of your eyes or eyelids; or
- severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
- nausea, vomiting, stomach pain;
- diarrhea or constipation; or
- tired feeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Vectibix (panitumumab injection for intravenous use) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about panitumumab (Vectibix)?
Before you receive panitumumab, tell your doctor if you have any allergies or breathing problems.
Panitumumab may cause severe skin problems such as acne, itching, redness, skin rash, dryness, peeling, cracking, or oozing, and swelling or infection around your fingernails or toenails. More severe forms of skin problems can lead to widespread infection and possibly death. Seek emergency medical attention at the first sign of any skin rash.
Some people receiving a panitumumab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, itchy, short of breath, or if you have a fever or chills during the injection.
The side effects of panitumumab may not appear when you first start using the medication. Severe skin or eye reactions may occur up to 2 weeks after the start of your treatment. These effects may not clear up for weeks or even months after you stop receiving panitumumab.
Avoid exposure to sunlight or tanning beds. Panitumumab can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
You may have irregular menstrual periods while receiving panitumumab.
Use birth control to prevent pregnancy while you are receiving panitumumab, whether you are a man or a woman. Panitumumab use by either parent may cause birth defects. Continue using birth control for 6 months after you stop receiving this medication.
Additional Vectibix Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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