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Cancer is the uncontrolled growth of abnormal cells anywhere in a body. The abnormal cells are termed cancer cells, malignant cells, or tumor cells. Many cancers and the abnormal cells that compose the cancer tissue are further identified by the name of the tissue that the abnormal cells originated from (for example, breast cancer, lung cancer, colon cancer). Cancer is not confined to humans; animals and other living organisms can get cancer. Below is a schematic that shows normal cell division and how when a cell is damaged or altered without repair to its system, the cell usually dies. Also shown is what can occur when such damaged or unrepaired cells do not die and become cancer cells and proliferate with uncontrolled growth; a mass of cancer cells develop. Frequently, cancer cells can break away from this original mass of cells, travel through the blood and lymph systems, and lodge in other organs where they can again repeat the ...
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Medical Editor: John P. Cunha, DO, FACOEP
Velcade (bortezomib) is used to treat multiple myeloma and mantle cell lymphoma, and is sometimes given after other cancer medications have been tried without successful treatment. It is an antineoplastic agent. Common side effects include dizziness, lightheadedness, nausea, vomiting, loss of appetite, diarrhea, constipation, tiredness, weakness, or blurred vision.
The recommended starting dose of Velcade is 1.3 mg/m². It may be administered intravenously (IV) at a concentration of 1 mg/mL, or subcutaneously (under the skin) at a concentration of 2.5 mg/mL. Velcade for Injection is administered in combination with oral melphalan and oral prednisone for nine 6-week treatment cycles. Velcade may interact with dexamethasone, rifabutin, rifampin, rifapentine, St. John's wort, antibiotics, antifungals, antidepressants, barbiturates, diabetes medications you take by mouth, HIV/AIDS medicine, medicines to treat narcolepsy, or seizure medication. Tell your doctor all medications you are taking. Velcade is not recommended for use during pregnancy. It may cause harm to a fetus. Use reliable form(s) of birth control during treatment with this drug. It is not known whether this drug passes into breast milk. Breast-feeding is not recommended while using this drug due to the potential risk to the nursing infant.
Our Velcade (bortezomib) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
VELCADE® (bortezomib) for Injection is indicated for the treatment of patients with multiple myeloma.
VELCADE(bortezomib) for Injection is indicated for the treatment of patients with mantle cell lymphoma who have received at least 1 prior therapy.
Read the complete drug monograph for Velcade »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Read the complete patient information for Velcade »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
HOW TO USE: This medication is given by injection into a vein by a healthcare professional. The dosage is based on your medical condition and response to therapy.
It is important to drink plenty of fluids while you are being treated with this drug to prevent becoming dehydrated. Read the Patient Information Leaflet that comes with this drug, and consult yo...
Read the complete consumer information for Velcade »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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