July 29, 2016
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Velcade Patient Information including How Should I Take

What should I discuss with my healthcare provider before receiving bortezomib (Velcade)?

You should not use this medication if you are allergic to bortezomib, mannitol, or boron.

To make sure bortezomib is safe for you, tell your doctor if you have:

  • diabetes;
  • liver disease;
  • kidney disease, or if you are on dialysis;
  • a bleeding or blood clotting disorder;
  • a low level of platelets or white or red blood cells;
  • heart disease, congestive heart failure;
  • herpes or a history of shingles;
  • high or low blood pressure; or
  • nerve problems such as numbness, burning, pain, or tingly feeling.

FDA pregnancy category D. Do not use bortezomib if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether bortezomib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using bortezomib.

How is bortezomib given (Velcade)?

Bortezomib is injected into a vein through an IV.

You will receive this injection in a clinic or hospital setting. A doctor, nurse, or other healthcare provider will give you this injection.

Bortezomib is usually injected 2 times a week for 2 weeks, followed by 10 days without an injection. Bortezomib may also be given once a week for 4 weeks followed by 13 days without an injection. Follow your doctor's instructions about your individual dosing schedule.

Bortezomib can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.

Side Effects Centers

Velcade - User Reviews

Velcade User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Velcade sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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