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Veltin

What is acne?

Acne (acne vulgaris, common acne) is a disease of the hair follicles of the face, chest, and back that affects almost all males and females during puberty; the only exception being teenage members of a few primitive isolated tribes living in Neolithic societies. It is not caused by bacteria, although bacteria play a role in its development. It is not unusual for some women to develop acne in their mid- to late-20s.

Acne appears on the skin as...

  • congested pores ("comedones"), also known as blackheads or whiteheads,
  • tender red bumps also known as pimples or zits,
  • pustules, and occasionally as
  • cysts (deep pimples, boils).

You can do a lot to treat your acne using products available at a drugstore or cosmetic counter that do not require a prescription. However, for tougher cases of acne, you should consult a physician for treatment options.

What...

Veltin

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VELTIN™
(clindamycin phosphate and tretinoin) Gel

DRUG DESCRIPTION

VELTIN™ (clindamycin phosphate and tretinoin) Gel, 1.2%/0.025%, is a fixed combination of two solubilized active ingredients in an aqueous based gel. Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.

The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(l-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate). The structural formula for clindamycin phosphate is represented below:

Clindamycin phosphate:

Clindamycin phosphate structural formula illustration

Molecular Formula: C18H34ClN2O8PS                Molecular Weight: 504.97

The chemical name for tretinoin is all-trans 3,7-dimethyl-9-(2,6,6-trimethyl-l-cyclohexen-l-yl)-2,4,6,8-nonatetraenoic acid. It is a member of the retinoid family of compounds.

The structural formula for tretinoin is represented below:

Tretinoin:

Tretinoin structural formula illustration

Molecular Formula: C20H28O2           Molecular Weight: 300.44

VELTIN (clindamycin phosphate and tretinoin gel) Gel contains the following inactive ingredients: butylated hydroxytoluene, carbomer 940, anhydrous citric acid, edetate disodium, methylparaben, laureth 4, propylene glycol, tromethamine, and purified water.

Last reviewed on RxList: 8/5/2010
This monograph has been modified to include the generic and brand name in many instances.

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