(Generic versions may still be available.)
The active component of VENTOLIN Inhalation Solution is albuterol sulfate, USP, the racemic form of albuterol and a relatively selective beta2-adrenergic bronchodilator (see CLINICAL PHARMACOLOGY). It has the chemical name a1-[(tert-butylamino)methyl] -4-hydroxy-m-xylene-a, a'-diol sulfate (2:1)(salt) and the following chemical structure:
Albuterol sulfate has a molecular weight of 576.7, and the empirical formula is (C13H21NO3)2·H2SO4.
Albuterol sulfate is a white crystalline powder, soluble in water and slightly soluble in ethanol.
The World Health Organization recommended name for albuterol base is salbutamol.
VENTOLIN Inhalation Solution, 0.5% is in concentrated form. Dilute the appropriate volume of the solution (see DOSAGE AND ADMINISTRATION) with sterile normal saline solution to a total volume of 3 mL and administer by nebulization.
Each milliliter of VENTOLIN Inhalation Solution contains 5 mg of albuterol (as 6 mg of albuterol sulfate) in an aqueous solution containing benzalkonium chloride; sulfuric acid is used to adjust the pH to between 3 and 5. VENTOLIN Inhalation Solution contains no sulfiting agents. It is supplied in a 20-mL amber glass bottle.
VENTOLIN Inhalation Solution is a clear, colorless to light yellow solution.
Last reviewed on RxList: 12/17/2004
This monograph has been modified to include the generic and brand name in many instances.
Additional Ventolin Solution Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Allergies & Asthma
Improve treatments & prevent attacks.