Ventolin Syrup (Albuterol Sulfate Syrup) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Ventolin Syrup

Chronic Obstructive Pulmonary Disease »

What is COPD?

Chronic obstructive pulmonary disease (COPD) is comprised primarily of three related conditions - chronic bronchitis, chronic asthma, and emphysema. In each condition there is chronic obstruction of the flow of air through the airways and out of the lungs, and the obstruction generally is permanent and may be progressive over time.

While asthma features obstruction to the flow of air out of the lungs, usually, the obstruction is reversible. Between "attacks" of asthma the flow of air through the airways typically is normal. These patients do not have COPD. However, if asthma is left untreated, the chronic inflammation associated with this disease can cause the airway obstruction to become fixed. That is, between attacks, the asthmatic patient may then have abnormal air flow. This process is referred to as lung remodeling. These asthma patients with a fixed component of airway obstruction are also considered to have COPD.

Often patien...

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

DRUG DESCRIPTION

VENTOLIN Syrup (albuterol sulfate syrup) contains albuterol sulfate, USP, the racemic form of albuterol, a relatively selective beta₂-adrenergic bronchodilator. Albuterol sulfate has the chemical name a1-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-a,a¹-diol sulfate (2:1) (salt), and the following chemical structure:

The molecular weight of albuterol sulfate is 576.7, and the empirical formula is (C₁₃H₂₁NO₃)₂·H₂SO₄. Albuterol sulfate is a white crystalline powder, soluble in water and slightly soluble in ethanol. The World Health Organization†s recommended name for albuterol base is salbutamol.

VENTOLIN Syrup (albuterol sulfate syrup) for oral administration contains 2 mg of albuterol as 2.4 mg of albuterol sulfate in each teaspoonful (5 mL). The inactive ingredients for VENTOLIN Syrup (albuterol sulfate syrup) include: citric acid, USP anhydrous; FD&C Yellow No. 6; flavor strawberry artificial F-8636; hydroxypropyl methylcellulose 2906 or 2910, USP; saccharin, NF; sodium benzoate, NF; sodium citrate, USP dihydrate; and water purified, USP. The pH of the syrup is between 3.0 and 4.5.

Last reviewed on RxList: 12/17/2004
This monograph has been modified to include the generic and brand name in many instances.