"The cystic fibrosis (CF) drug Orkambi (Vertex Pharmaceuticals) has received a green light from the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP).
Orkambi is a fixed-dose oral combination "...
(Generic versions may still be available.)
(mebendazole) Chewable Tablets
VERMOX® (mebendazole) is a (synthetic) broad-spectrum anthelmintic available as chewable tablets, each containing 100 mg of mebendazole. Inactive ingredients are: colloidal silicon dioxide, corn starch, hydrogenated vegetable oil, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, sodium saccharin, sodium starch glycolate, talc, tetrarome orange, and FD&C yellow No. 6.
Mebendazole is methyl 5-benzoylbenzimidazole-2-carbamate. Mebendazole is a white to slightly yellow powder with a molecular weight of 295.29. It is less than 0.05% soluble in water, dilute mineral acid solutions, alcohol, ether and chloroform, but is soluble in formic acid.
What are the possible side effects of mebendazole (Vermox)?
Stop taking mebendazole and seek emergency medical attention if you experience an allergic reaction (swelling of your lips, tongue, or face; shortness of breath; closing of your throat; or hives).
Other, less serious side effects may be more likely to occur. Continue to take mebendazole and talk to your doctor if you experience abdominal pain, diarrhea, or a fever.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...
What are the precautions when taking mebendazole (Vermox)?
Before taking mebendazole, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Tell your doctor your medical history, especially of: low blood count (anemia), liver disease, intestinal problems (e.g., Crohn's disease, ulcerative colitis).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is not known whether this drug passes into breast milk. Consult your doctor before...
Last reviewed on RxList: 5/13/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Vermox Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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