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Pinworm infection is an infection of the large intestine and anal area by a small, white parasite that resembles a "worm." The medical name for the parasite is Enterobius vermicularis, but it is commonly termed a pinworm in both the lay and medical literature. These parasites are also termed seatworms or threadworms, and the infections is medically termed enterobiasis or helminthiasis. Pinworms and other parasitic worms (as a group are termed helminths) feed off of the host animal by adsorbing nutrients from the host animal. Pinworm infections are the most common helminth infection that occurs in the US. The US Centers for Disease Control and Prevention (CDC) estimates about 40 million people are infected with pinworms currently in the US.
Pinworm is the most common worm infection in the United States, and the majority of pinworm infections worldwide occ...
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Following administration of 100 mg twice daily for three consecutive days, plasma levels of VERMOX® (mebendazole) and its primary metabolite, the 2-amine, do not exceed 0.03 µg/mL and 0.09 µg/mL, respectively. All metabolites are devoid of anthelmintic activity. In man, approximately 2% of administered VERMOX® (mebendazole) is excreted in urine and the remainder in the feces as unchanged drug or a primary metabolite.
Mode of Action
VERMOX® (mebendazole) inhibits the formation of the worms' microtubules and causes the worms' glucose depletion.
Last reviewed on RxList: 5/13/2008
This monograph has been modified to include the generic and brand name in many instances.
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