VESIcare

Drug Description
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VESIcare®
(solifenacin succinate) Tablets

DRUG DESCRIPTION

VESIcare® (solifenacin succinate) is a muscarinic receptor antagonist. Chemically, solifenacin succinate is butanedioic acid, compounded with (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-iso- quinolinecarboxylate (1:1) having an empirical formula of C23H26N2O2 C4H6O4, and a molecular weight of 480.55. The structural formula of solifenacin succinate is:

VESIcare® (solifenacin succinate)  Structural Formula Illustration

Solifenacin succinate is a white to pale-yellowish-white crystal or crystalline powder. It is freely soluble at room temperature in water, glacial acetic acid, dimethyl sulfoxide, and methanol. Each VESIcare tablet contains 5 or 10 mg of solifenacin succinate and is formulated for oral administration. In addition to the active ingredient solifenacin succinate, each VESIcare tablet also contains the following inert ingredients: lactose monohydrate, corn starch, hypromellose 2910, magnesium stearate, talc, polyethylene glycol 8000 and titanium dioxide with yellow ferric oxide (5 mg VESIcare tablet) or red ferric oxide (10 mg VESIcare tablet).

Last updated on RxList: 1/8/2009

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ENABLEX is a prescription medicine used in adults to treat the following symptoms due to a condition called overactive bladder:

  • · having a strong need to go to the bathroom right away (also called "urgency")
  • · leaks or wetting accidents (also called "urinary incontinence")
  • · having to go to the bathroom too often (also called "urinary frequency")

IMPORTANT SAFETY INFORMATION

You should not take once-daily ENABLEX if you have certain types of stomach problems, glaucoma, or have trouble emptying your bladder. Side effects of ENABLEX include blurred vision, and more commonly dry mouth, constipation, indigestion, and abdominal pain. Use caution when doing certain activities until you know how ENABLEX affects you.


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