"Jan. 25, 2013 -- The FDA has approved Oxytrol for Women, the first over-the-counter treatment for overactive bladder in women 18 and older.
The condition affects more than 20 million American women, according to Merck, the drug's manu"...
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Details with Side Effects
Overdosage with VESIcare can potentially result in severe anticholinergic effects and should be treated accordingly. The highest dose ingested in an accidental overdose of solifenacin succinate was 280 mg in a 5-hour period. This case was associated with mental status changes. Some cases reported a decrease in the level of consciousness.
Intolerable anticholinergic side effects (fixed and dilated pupils, blurred vision, failure of heel-to-toe exam, tremors and dry skin) occurred on day 3 in normal volunteers taking 50 mg daily (5 times the maximum recommended therapeutic dose) and resolved within 7 days following discontinuation of drug.
VESIcare is contraindicated in patients with:
- urinary retention [see WARNINGS AND PRECAUTIONS],
- gastric retention [see WARNINGS AND PRECAUTIONS],
- uncontrolled narrow-angle glaucoma [see WARNINGS AND PRECAUTIONS], and
- in patients who have demonstrated hypersensitivity to the drug [see ADVERSE REACTIONS].
Last reviewed on RxList: 11/5/2013
This monograph has been modified to include the generic and brand name in many instances.
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