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Vexol® 1 %
(rimexolone) Ophthalmic Suspension


VEXOL® 1% Ophthalmic Suspension is a sterile, multi-dose topical ophthalmic suspension containing the corticosteroid, rimexolone. Rimexolone is a white, water-insoluble powder with an empirical formula of C24H34O3 and a molecular weight of 370.53. Its chemical name is 11α-Hydroxy-16β, 17β-dimethyl-17-propionylandrosta-l,4-diene-3-one. The chemical structure of rimexolone is presented below:

VEXOL (rimexolone) structural formula illustration

Each mL Contains: Active ingredient: rimexolone 10 mg (1%). Preservative: benzalkonium chloride 0.01%. Inactive ingredients: carbomer 974P, polysorbate 80, sodium chloride, edetate disodium, sodium hydroxide and/or hydrochloric acid (to adjust pH) and purified water.

The pH of the suspension is 6.0 to 8.0 and the tonicity is 260 to 320 mOsmol/kg.

What are the possible side effects of rimexolone ophthalmic (Vexol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using rimexolone ophthalmic and call your doctor at once if you have a serious side effect such as:

  • vision changes, eye pain, or seeing halos around lights;
  • pain behind your eyes;
  • feeling like something is in your eye; or
  • eye swelling, redness, itching, severe discomfort, crusting or drainage (may be signs of infection).

Less serious side effects may...

Read All Potential Side Effects and See Pictures of Vexol »

What are the precautions when taking rimexolone (Vexol)?

Before using rimexolone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye infections, cataracts, glaucoma (open-angle type), severe nearsightedness (myopia), diabetes.

After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs,...

Read All Potential Precautions of Vexol »

Last reviewed on RxList: 3/7/2012
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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