"Targeting cholesterol metabolism in the eye might help prevent a severe form of age-related macular degeneration (AMD), one of the most common causes of blindness in older Americans, according to indications in a study in mice, which was suppo"...
Vexol® 1 %
(rimexolone) Ophthalmic Suspension
VEXOL® 1% Ophthalmic Suspension is a sterile, multi-dose topical ophthalmic
suspension containing the corticosteroid, rimexolone. Rimexolone is a white,
water-insoluble powder with an empirical formula of C24H34O3
and a molecular weight of 370.53. Its chemical name is 11α-Hydroxy-16β,
17β-dimethyl-17-propionylandrosta-l,4-diene-3-one. The chemical structure
of rimexolone is presented below:
Each mL Contains: Active ingredient: rimexolone 10 mg (1%). Preservative: benzalkonium chloride 0.01%. Inactive ingredients: carbomer 974P, polysorbate 80, sodium chloride, edetate disodium, sodium hydroxide and/or hydrochloric acid (to adjust pH) and purified water.
The pH of the suspension is 6.0 to 8.0 and the tonicity is 260 to 320 mOsmol/kg.
What are the possible side effects of rimexolone ophthalmic (Vexol)?
Serious side effects are not expected with this medication. Rarely, an increase in the pressure inside of the eye, formation of cataracts, or perforation of the cornea have been reported. Talk to your doctor about any possible side effects.
More commonly, some burning, stinging, irritation, itching, redness, blurred vision, or sensitivity to light may occur.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...
What are the precautions when taking rimexolone (Vexol)?
Before using rimexolone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye infections, cataracts, glaucoma (open-angle type), severe nearsightedness (myopia), diabetes.
After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs,...
Last reviewed on RxList: 3/7/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Vexol Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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