May 28, 2017
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(leuprolide acetate implant)

Important Information for Patients Using Viadur® (leuprolide acetate implant) for the treatment of symptoms of advanced prostate cancer.

Please read this information before you start using Viadur® (leuprolide acetate implant) . Each time another Viadur® (leuprolide acetate implant) is inserted, check the patient information leaflet for any new information. Remember, this information does not take the place of your doctor's instructions. Ask your doctor or pharmacist if you have questions or want more information about Viadur® (leuprolide acetate implant) .

What is Viadur® (leuprolide acetate implant) ?

Viadur® (leuprolide acetate implant) is a drug-delivery system that contains the drug leuprolide and is placed under the skin. It looks like a small, thin metal tube. After it is placed under the skin, Viadur® (leuprolide acetate implant) delivers leuprolide to your body continuously for 12 months.

How does Viadur® (leuprolide acetate implant) work?

Leuprolide, the active medication in Viadur® (leuprolide acetate implant) , works by reducing the testosterone produced by the testicles. This lowers the amount of testosterone in the body. Testosterone appears to be needed by prostate cancer cells. Usually prostate cancer shrinks or stops growing when the body's supply of testosterone is lowered.

By lowering the amount of testosterone in the body, Viadur® (leuprolide acetate implant) may help relieve the pain, urinary problems, and other symptoms of prostate cancer. However, Viadur® (leuprolide acetate implant) is not a cure for prostate cancer. Once Viadur® (leuprolide acetate implant) is removed by your doctor, your body will start producing testosterone again.

How is Viadur® (leuprolide acetate implant) given?

Viadur® (leuprolide acetate implant) will be placed under the skin of your upper, inner arm. The doctor will numb your arm, make a small incision, and then place Viadur® (leuprolide acetate implant) under the skin. The incision will be closed with special surgical tape and covered with a bandage. You should keep the bandage in place for a few days until the incision heals.

After 12 months, Viadur® (leuprolide acetate implant) must be removed and may be replaced with a new Viadur® (leuprolide acetate implant) by your doctor.

What should I avoid while Viadur® (leuprolide acetate implant) is inserted?

After Viadur® (leuprolide acetate implant) is inserted, keep the site clean and dry for 24 hours. Do not bathe or swim for 24 hours. Avoid heavy lifting and physical activity for 48 hours. Avoid bumping the site for a few days. After the cut has healed, you should be able to go back to your normal activities.

What should I know about using Viadur® (leuprolide acetate implant) ?

  • If you notice unusual bleeding, redness or pain at the insertion site, contact your doctor.
  • In the first few weeks of treatment, if you experience increased pain throughout your body, weakness, or numbness, contact your doctor.
  • X-rays and MRI do not affect Viadur® (leuprolide acetate implant) .
  • Viadur® (leuprolide acetate implant) is seen on X-rays. Slight image distortion around Viadur® (leuprolide acetate implant) may occur during MRI procedures.
  • Viadur® (leuprolide acetate implant) must be removed and may be replaced after 12 months.

Who should NOT use Viadur® (leuprolide acetate implant) ?

Do not use Viadur® (leuprolide acetate implant) if you are allergic to the drug leuprolide.

Do not use Viadur® (leuprolide acetate implant) if you are a woman. Viadur® (leuprolide acetate implant) is not approved for use by women of any age. Furthermore, use of Viadur® (leuprolide acetate implant) in a woman who is or may become pregnant may cause harm to the baby. You may lose your baby through a miscarriage if the drug is used while you are pregnant.

Viadur® (leuprolide acetate implant) was not studied in children and should not be used in children.

What are the most common side effects of Viadur® (leuprolide acetate implant) ?

The most common side effects related to Viadur® (leuprolide acetate implant) were hot flashes, lack of energy, depression, sweating, headache, bruising, and breast enlargement.

Prostate cancer-related symptoms may become worse during the first few weeks of treatment.

Like other similar treatment options, Viadur® (leuprolide acetate implant) may cause impotence.

There may be some pain and discomfort during and after Viadur® (leuprolide acetate implant) insertion and removal. Bruising may occur. Reactions, such as itching and redness, are usually mild and heal without treatment within two weeks. If they do not heal, contact your doctor.

There is a chance that your bones may become thinner if you use this type of drug for long periods of time. Ask your doctor if this is a risk for you.

This list is not a complete list of all the possible side effects. If you need more information, or are worried about these or other side effects, talk to your doctor or pharmacist.

What tests will my doctor perform during my treatment with Viadur® (leuprolide acetate implant) ?

Your doctor may measure blood levels of testosterone and prostate-specific antigen (PSA) during your treatment with Viadur® (leuprolide acetate implant) .

Can I take Viadur® (leuprolide acetate implant) with other medications?

Tell your doctor or pharmacist about any medicines that you are taking, including Viadur® (leuprolide acetate implant) , prescription, non-prescription, and herbal remedies. Do not start taking a new medicine before checking with your doctor or pharmacist.

For more information on Viadur® (leuprolide acetate implant) , talk to your doctor or pharmacist, call 1-800288-8371 between 8:30 AM and 5 PM Eastern Standard Time, or visit www.VIADUR (leuprolide acetate implant) .com on the Internet.

Last reviewed on RxList: 3/20/2017
This monograph has been modified to include the generic and brand name in many instances.

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