Vicodin ES (Hydrocodone Bitartrate and Acetaminophen) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Vicodin ES

Neck Pain »

What is neck pain? What are causes and risk factors for neck pain?

Pain located in the neck is a common medical condition. Neck pain can come from a number of disorders and diseases of any tissues in the neck. Examples of common conditions producing neck pain are degenerative disc disease, neck strain, neck injury such as in whiplash, a herniated disc, or a pinched nerve. Neck pain can come from common infections, such as virus infection of the throat, leading to lymph gland swelling and neck pain. Neck pain can also come from rare infections, such as tuberculosis of the neck and bone infection of the spine in the neck (osteomyelitis and septic discitis), and meningitis (often accompanied by neck stiffness). Neck pain can also come from conditions directly affecting the muscles of the neck, such as fibromyalgia and polymyalgia rheumatica. Neck pain is also referred to as cervical pain.

Risk factors for neck pain include injury from involvement in contact spor...

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Vicodin ES

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Vicodin ES®
(hydrocodone bitartrate and acetaminophen) Tablets, USP
7.5 mg/750 mg

DRUG DESCRIPTION

Hydrocodone bitartrate and acetaminophen is supplied in tablet form for oral administration.

Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. It is affected by light. The chemical name is: 4,5α -epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5). It has the following structural formula:

Vicodin ES (hydrocodone bitartrate and acetaminophen)

C₁₈H₂₁NO₃·C₄H₆O₆·2½H₂O M.W.= 494.50

Acetaminophen, 4'-hydroxyacetanilide, a slightly bitter, white, odorless, crystalline powder, is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula:

C₈H₉NO₂ M.W. 151.16

Each VICODIN ES (hydrocodone bitartrate and acetaminophen) Tablet contains:
Hydrocodone Bitartrate 7.5 mg
Acetaminophen 750 mg

In addition each tablet contains the following inactive ingredients: Colloidal silicon dioxide, pregelatinized starch, magnesium stearate, croscarmellose sodium, povidone, and stearic acid.

Meets USP Dissolution Test 2.

What are the possible side effects of acetaminophen and hydrocodone?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
feeling light-headed, fainting;
confusion, fear, unusual thoughts or behavior;
seizure (convulsions);
problems with urination; or
nausea, stomach pain, loss of appetite, itching, dark urine,...

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What are the precautions when taking hydrocodone bitartrate and acetaminophen (Vicodin ES)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other narcotics (such as morphine, codeine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (such as head injury, tumor, seizures), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), kidney disease, liver disease, mental/mood disorders (such as confusion, depression), personal or family history of regular use/abuse of drugs/alcohol, stomach/intestinal problems (such as blockage, constipation, diarrhea...

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Last reviewed on RxList: 3/14/2007
This monograph has been modified to include the generic and brand name in many instances.