May 30, 2017
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Vicoprofen Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking hydrocodone and ibuprofen (Vicoprofen)?

You should not use this medication if you are allergic to hydrocodone or ibuprofen (Advil, Motrin), or other NSAIDs such as Aleve, Naprosyn, Celebrex, Arthrotec, Cataflam, Voltaren, Indocin, Mobic, and others.

Do not use hydrocodone and ibuprofen just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.

This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking hydrocodone and ibuprofen, especially in older adults.

To make sure you can safely take hydrocodone and ibuprofen, tell your doctor if you have any of these other conditions:

  • heart disease, congestive heart failure, high blood pressure, or a history of heart attack, stroke, or blood clot;
  • asthma or other breathing disorders;
  • liver or kidney disease;
  • a history of head injury or brain tumor;
  • stomach or intestinal disorder, history of stomach ulcer or bleeding;
  • underactive thyroid, Addison's disease or other adrenal gland disorder;
  • curvature of the spine;
  • an enlarged prostate or problems with urination; or
  • mental illness or a history of drug or alcohol addiction.

Hydrocodone may be habit forming and should be used only by the person for whom it was prescribed. Never share hydrocodone and ibuprofen with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

FDA pregnancy category C. Hydrocodone may cause breathing problems or addiction/withdrawal symptoms in a newborn. Taking ibuprofen during the last 3 months of pregnancy may harm the unborn baby. Do not take hydrocodone and ibuprofen during pregnancy unless your doctor has told you to.

It is not known whether hydrocodone and ibuprofen passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using hydrocodone and ibuprofen.

Older adults may be more likely to have side effects from this medicine.

How should I take hydrocodone and ibuprofen (Vicoprofen)?

Take exactly as prescribed. Never take hydrocodone and ibuprofen in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

If you need surgery, tell the surgeon ahead of time that you are using hydrocodone and ibuprofen. You may need to stop using the medicine for a short time.

Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Hydrocodone and ibuprofen is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side Effects Centers

Vicoprofen - User Reviews

Vicoprofen User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Vicoprofen sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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