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Vicoprofen Patient Information Including Side Effects

Brand Names: Ibudone, Reprexain, Vicoprofen

Generic Name: hydrocodone and ibuprofen (Pronunciation: hye dro KOE done and eye byoo PRO fen)

What is hydrocodone and ibuprofen (Vicoprofen)?

Hydrocodone is in a group of drugs called narcotic pain relievers.

Ibuprofen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Ibuprofen works by reducing hormones that cause inflammation and pain in the body.

The combination of hydrocodone and ibuprofen is used short-term to relieve severe pain. This medication is not for treating arthritis pain.

Hydrocodone and ibuprofen may also be used for other purposes not listed in this medication guide.

Hydrocodone-Ibuprofen 7.5 mg-200 mg-TEV

round, white, imprinted with 5161

Hydrocodone-Ibuprofen 7.5-200 mg-WAT

round, white, imprinted with IP 145

Reprexain 5 mg-200 mg

oval, white, imprinted with IP 146


round, white, imprinted with VP LOGO

What are the possible side effects of hydrocodone and ibuprofen (Vicoprofen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
  • sudden numbness or weakness, headache, confusion, or problems with vision, speech, or balance;
  • black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • swelling or rapid weight gain;
  • shallow breathing, slow heartbeat;
  • confusion, feeling light-headed, fainting;
  • easy bruising or bleeding;
  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • severe blistering, peeling, and red skin rash; or
  • fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions).

Less serious side effects may include:

  • headache, dizziness, drowsiness;
  • mild nausea, vomiting, upset stomach, constipation, diarrhea;
  • blurred vision; or
  • dry mouth.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the Vicoprofen (hydrocodone and ibuprofen) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about hydrocodone and ibuprofen (Vicoprofen)?

Ibuprofen can increase your risk of heart attack or stroke. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG). Seek emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

Ibuprofen can also increase your risk of serious effects on the stomach or intestines. These conditions can be fatal and can occur without warning at any time while you are taking ibuprofen. Call your doctor at once if you have black, bloody, or tarry stools, or if you cough up blood or vomit that looks like coffee grounds.

Hydrocodone may be habit-forming and should be used only by the person this medicine was prescribed for. Keep the medication in a secure place where others cannot get to it.

Avoid drinking alcohol while taking hydrocodone and ibuprofen. Alcohol may increase your risk of stomach bleeding while taking ibuprofen.

Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Side Effects Centers

Vicoprofen - User Reviews

Vicoprofen User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Vicoprofen sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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