"Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist
Entry inhibitors block HIV entry into CD4+ cells.
The only drug in this class "...
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
DIDANOSINE (DDI) SOLUTION - ORAL
COMMON BRAND NAME(S): Videx
WARNING: Rarely, didanosine has caused a severe (sometimes fatal) pancreas problem (pancreatitis) when used alone or with other HIV medicines. Immediately tell your doctor if you develop symptoms of pancreatitis (persistent nausea/vomiting, stomach/abdominal/back pain).
Rarely, didanosine has caused a severe (sometimes fatal) liver and blood problem (lactic acidosis). Immediately tell your doctor if you develop symptoms of liver problems (persistent nausea, stomach/abdominal pain, dark urine, yellowing eyes/skin) or lactic acidosis (rapid breathing, drowsiness, muscle aches, severe weakness). Pregnant women with HIV may be more likely to have this problem. Liver and pancreas problems may be more likely if didanosine is used in combination with hydroxyurea and/or another HIV medicine (stavudine).
USES: This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Didanosine belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI.
Didanosine is not a cure for HIV infection. To decrease your risk of spreading HIV disease to others, do all of the following: (1) continue to take all HIV medications exactly as prescribed by your doctor, (2) always use an effective barrier method (latex or polyurethane condoms/dental dams) during all sexual activity, and (3) do not share personal items (such as needles/syringes, toothbrushes, and razors) that may have contacted blood or other body fluids. Consult your doctor or pharmacist for more details.
HOW TO USE: Read the Medication Guide provided by your pharmacist before you start using didanosine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth usually 1-2 times a day on an empty stomach, at least 30 minutes before or 2 hours after a meal, or as directed by your doctor. Shake the bottle well before measuring each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
Didanosine solution is mixed by your pharmacist with an antacid to form a suspension. The antacid can interfere with your body's ability to absorb certain drugs, especially if you take them around the same time. These drugs include quinolone antibiotics (such as ciprofloxacin, levofloxacin), tetracycline antibiotics (such as doxycycline, minocycline), levodopa, thyroid medications (such as levothyroxine), azole antifungals (such as ketoconazole, itraconazole), and drugs for osteoporosis (bisphosphonates such as alendronate). This is not a complete list. Consult with your pharmacist how long you must wait between doses of your other medications and didanosine solution. Do not take other antacids or acid-lowering drugs (such as cimetidine, omeprazole, ranitidine) with this product without talking with your doctor first.
The dosage is based on your weight, medical condition, and response to treatment.
It is very important to continue taking this medication (and other HIV medications) exactly as prescribed by your doctor. Do not skip any doses. Do not increase your dose, take this drug more often than prescribed, or stop taking it (or other HIV medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of virus to increase, make the infection more difficult to treat (resistant), or worsen side effects.
This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time(s) each day.
Additional Videx Information
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