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Osteoarthritis facts

  • Osteoarthritis is a joint inflammation that results from cartilage degeneration.
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  • There is no blood test for the diagnosis of osteoarthritis.
  • The goal of treatment in osteoarthritis is to reduce joint pain and inflammation while improving and maintaining joint function.

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Osteoarthritis is a form of arthritis that features the breakdown and eventual loss of the cartilage of one or more joints. Cartilage is a protein substance that serves as a "cushion" between the bones of the joints. Among the over 100 different types of arthritis conditions, osteoarthritis is the most common, affecting over 25 million people in the United Stat...

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Vioxx

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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Vioxx Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Vioxx (rofecoxib) is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis and certain forms of juvenile rheumatoid arthritis; to manage acute pain in adults; to treat migraines; and to treat menstrual pain. It is in a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). The brand name Vioxx was withdrawn from the U.S. market in 2004 and is no longer available. Generic versions may still be available. Common side effects include dizziness, mild fatigue or weakness, or diarrhea.

Dosage of rofecoxib is based on your medical condition and response to therapy. Rofecoxib may interact with aspirin or other salicylates, over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, naproxen, or ketoprofen, diuretics (water pills), ACE inhibitors, steroids, blood thinners, methotrexate, theophylline, lithium, or rifampin. Tell your doctor all medications you are taking. This medication should not be taken in the third trimester of pregnancy because it may affect the formation of the baby's heart. Do not take rofecoxib without talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether this medication passes into breast milk. Consult your doctor before breast-feeding.

Our Vioxx (rofecoxib) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Vioxx Prescribing Information: Indications & Dosage

VIOXX (rofecoxib) is indicated:

For relief of the signs and symptoms of osteoarthritis.

For relief of the signs and symptoms of rheumatoid arthritis in adults.

For relief of the signs and symptoms of pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis (JRA) in patients 2 years and older and who weigh 10 kg (22 lbs) or more.

For the management of acute pain in adults.

For the treatment of primary dysmenorrhea.

For th...

Read the complete drug monograph for Vioxx »

What is Vioxx Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Vioxx Patient Information: Side Effects

Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; blood in your vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of your skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.

If you experience any of the following serious side effects, stop taking rofecoxib and seek medical treatment or contact your doctor immediately:

  • an allergic reaction (difficult...

Read the complete patient information for Vioxx »

What is Vioxx Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

Related Resources for Vioxx

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© Vioxx Patient Information is supplied by Cerner Multum, Inc. and Vioxx Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Additional Vioxx Information

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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