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- Clinician Information:
Vioxx Patient Information including How Should I Take
In this Article
- What is rofecoxib (Vioxx)?
- What are the possible side effects of rofecoxib (Vioxx)?
- What is the most important information I should know about rofecoxib (Vioxx)?
- What should I discuss with my healthcare provider before taking rofecoxib (Vioxx)?
- How should I take rofecoxib (Vioxx)?
- What happens if I miss a dose (Vioxx)?
- What happens if I overdose (Vioxx)?
- What should I avoid while taking rofecoxib (Vioxx)?
- What other drugs will affect rofecoxib (Vioxx)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking rofecoxib (Vioxx)?
The manufacturer of rofecoxib (Vioxx) has announced a voluntary withdrawal of the drug from the U.S. and worldwide market. This withdrawal is due to safety concerns of an increased risk of cardiovascular events (including heart attack and stroke) in patients taking rofecoxib.
Do not take rofecoxib without first talking to your doctor if you have experienced asthma, hives, or an allergic reaction after taking aspirin or another NSAID such as ibuprofen (Motrin, Advil, Nuprin), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis, Oruvail), diclofenac (Voltaren, Cataflam), diflunisal (Dolobid), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), celecoxib (Celebrex), valdecoxib (Bextra), or meloxicam (Mobic). You may experience a similar reaction to rofecoxib.
Before taking rofecoxib, tell your doctor if you
- drink alcohol;
- have ever had an ulcer or bleeding in your stomach;
- have liver disease;
- have kidney disease;
- have asthma;
- have congestive heart failure;
- have fluid retention;
- have heart disease;
- have high blood pressure;
- have a coagulation (bleeding) disorder or are taking an anticoagulant (blood thinner) such as warfarin (Coumadin); or
- are taking a steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others.
You may not be able to take rofecoxib, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions, or are taking any of the medicines, listed above.
Rofecoxib is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Rofecoxib should not be taken late in pregnancy (the third trimester) because it may affect the formation of the baby's heart. Do not take rofecoxib without first talking to your doctor if you are pregnant or could become pregnant during treatment.
It is not known whether rofecoxib passes into breast milk. Do not take rofecoxib without first talking to your doctor if you are breast-feeding.
If you are over the age of 65 years, you may be more likely to experience side effects from rofecoxib. You may require a lower dosage or special monitoring during treatment.
How should I take rofecoxib (Vioxx)?
Take rofecoxib exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Shake the rofecoxib suspension well before measuring a dose. Use a dose-measuring cup or spoon, not a regular table spoon, to measure the liquid form of rofecoxib to ensure that you measure the correct amount of medicine. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
Rofecoxib can be taken with or without food or milk.
Store rofecoxib at room temperature away from moisture and heat.
Additional Vioxx Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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