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Acute massive overdosage by oral ingestion of the ophthalmic ointment has not occurred. However, the rapid deamination to arabinosylhypoxanthine should preclude any difficulty. The oral LD50 for vidarabine is greater than 5020 mg/kg in mice and rats. No untoward effects should result from ingestion of the entire contents of the tube.
Overdosage by ocular instillation is unlikely because any excess should be quickly expelled from the conjunctival sac.
VIRA-A (vidarabine) Ophthalmic Ointment, 3%, is contraindicated in patients who develop hypersensitivity reactions to it.
Last reviewed on RxList: 4/8/2009
This monograph has been modified to include the generic and brand name in many instances.
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