"An investigational therapeutic genital herpes vaccine has shown significant antiviral activity in a phase 2 trial, said researchers speaking here at the American Academy of Dermatology (AAD) 74th Annual Meeting.
The vaccine, currently"...
VIROPTIC is the brand name for trifluridine (also known as trifluorothymidine, F3TdR,F3T), an antiviral drug for topical treatment of epithelial keratitis caused by herpes simplex virus. The chemical name of trifluridine is αα α -trifluorothymidine; it has the following structural formula:
VIROPTIC sterile ophthalmic solution contains 1% trifluridine in an aqueous solution with acetic acid and sodium acetate (buffers), sodium chloride, and thimerosal 0.001% (added as a preservative). The pH range is 5.5 to 6.0 and osmolality is approximately 283 mOsm.
What are the possible side effects of trifluridine ophthalmic (Trifluridine, Viroptic)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using trifluridine ophthalmic and call your doctor at once if you have any of these serious side effects:
- severe swelling around your eyes;
- tunnel vision; or
- severe pain, burning, or other irritation of your eyes.
Keep using the medication and talk to your doctor if you have any of these less serious side effects:
- mild eye pain, burning,...
What are the precautions when taking trifluridine (Viroptic)?
Before using trifluridine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye problems (e.g., glaucoma).
After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is not known whether this drug passes...
Last reviewed on RxList: 4/13/2009
This monograph has been modified to include the generic and brand name in many instances.
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