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Visicol

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Visicol® (sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous)
(sodium phosphate monobasic monohydrate, USP, and sodium phosphate dibasic anhydrous, USP) Tablets

WARNINGS

There have been rare, but serious reports of acute phosphate nephropathy in patients who received oral sodium phosphate products for colon cleansing prior to colonoscopy. Some cases have resulted in permanent impairment of renal function and some patients required long-term dialysis. While some cases have occurred in patients without identifiable risk factors, patients at increased risk of acute phosphate nephropathy may include those with increased age, hypovolemia, increased bowel transit time (such as bowel obstruction), active colitis, or baseline kidney disease, and those using medicines that affect renal perfusion or function (such as diuretics, angiotensin converting enzyme [ACE] inhibitors, angiotensin receptor blockers [ARBs], and possibly nonsteriodal anti-inflammatory drugs [NSAIDs]). See WARNINGS.

It is important to use the dose and dosing regimen as recommended (pm/am split dose). See DOSAGE AND ADMINISTRATION.

DRUG DESCRIPTION

Visicol® (sodium phosphate monobasic monohydrate, USP, and sodium phosphate dibasic anhydrous, USP) is a purgative used to clean the colon prior to colonoscopy. Visicol® (sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous) Tablets are white to off-white compressed tablets, with a monogram "I" on each side of the upper surface and a plain lower surface. Each tablet contains 1.102 grams of sodium phosphate monobasic monohydrate, USP and 0.398 grams of sodium phosphate dibasic anhydrous, USP for a total of 1.5 grams of sodium phosphate per tablet. Inert ingredients include microcrystalline cellulose (MCC), NF; magnesium stearate, NF; and colloidal silicon dioxide, NF. Visicol® (sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous) is gluten-free.

The structural and molecular formulae and molecular weights of the active ingredients are shown below:

  • Sodium phosphate monobasic monohydrate, USP

Sodium phosphate monobasic monohydrate Structural Formula Illustration

Molecular Formula: NaH2PO4·H2O

Molecular Weight: 137.99

  • Sodium phosphate dibasic anhydrous, USP

Sodium phosphate dibasic anhydrous Structural Formula Illustration

Molecular Formula: Na2HPO4

Molecular Weight: 141.96

Visicol® (sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous) Tablets are for oral administration only.

What are the possible side effects of sodium biphosphate and sodium phosphate (Fleet Enema, Fleet Enema for Children, OsmoPrep, Visicol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • rectal bleeding;
  • no bowel movement after use;
  • sores or ulcers around your rectum;
  • seizure (black-out or convulsions);
  • fast, slow, or uneven...

Read All Potential Side Effects and See Pictures of Visicol »

What are the precautions when taking sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous (Visicol)?

See also How to Use section.

Before taking sodium phosphate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart failure, irregular heartbeat, QT prolongation in the EKG, chest pain, heart attack or heart surgery within the last 3 months), stomach/abdominal problems (such as blockage, severe constipation), gastric bypass/stapling, irritable bowel disease/colitis, low blood minerals, severe loss of body water (dehydration), kidney problems, liver problems (such as...

Read All Potential Precautions of Visicol »

Last reviewed on RxList: 4/17/2009
This monograph has been modified to include the generic and brand name in many instances.

Additional Visicol Information

Visicol - User Reviews

Visicol User Reviews

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Here is a collection of user reviews for the medication Visicol sorted by most helpful. Patient Discussions FAQs

See User Reviews

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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